Kirsten Jensen

TL;DR: The data on the known PML isoforms and splice variants are summarized and a new unifying nomenclature is presented, suggesting that these sequences are indispensable for function, but differ in their C-terminal sequences.

TL;DR: The results indicate the existence of a cross‐talk between PML‐ and p53‐dependent growth suppression pathways, implying an important role for NBs and their resident proteins as modulators of p53 functions.

TL;DR: A rapid and completely in vitro method to generate DNA templates for cell-free systems, bypassing the need for DNA template generation and amplification from living cells is devised, providing a valuable tool for rapidly prototyping libraries of DNA regulatory elements for synthetic biology.

TL;DR: A bacterial strain that is readily amenable to genetic engineering and produces high quantities of bacterial cellulose in low-cost media is described and sequenced and genetic circuits that enable functionalization and patterning of heterologous gene expression within the cellulose matrix are demonstrated.

TL;DR: A rapid and automated methodology for characterizing new DNA parts from a nonmodel bacterium using cell-free transcription–translation using Bayesian parameter inference and a Bayesian approach to infer ordinary differential equation model parameters by simultaneously using time-course data from multiple experimental conditions is presented.