There is, I think, something ethereal about i —the square root of minus one. I remember first hearing about it at school. It seemed an odd beast at that time—an intruder hovering on the edge of reality.

Usually familiarity dulls this sense of the bizarre, but in the case of i it was the reverse: over the years the sense of its surreal nature intensified. It seemed that it was impossible to write mathematics that described the real world in …

I and i

Co-Planar Stereotaxic Atlas of the Human Brain—3-Dimensional Proportional System: An Approach to Cerebral Imaging, J. Talairach, P. Tournoux. Georg Thieme Verlag, New York (1988), 122 pp., 130 figs. DM 268

Part I. Experimental Studies: 2. Experiment in psychology 3. Experiments on perceiving III Experiments on imaging 4-8. Experiments on remembering: (a) The method of description (b) The method of repeated reproduction (c) The method of picture writing (d) The method of serial reproduction (e) The method of serial reproduction picture material 9. Perceiving, recognizing, remembering 10. A theory of remembering 11. Images and their functions 12. Meaning Part II. Remembering as a Study in Social Psychology: 13. Social psychology 14. Social psychology and the matter of recall 15. Social psychology and the manner of recall 16. Conventionalism 17. The notion of a collective unconscious 18. The basis of social recall 19. A summary and some conclusions.

Remembering. A Study in Experimental and Social Psychology, Cambridge (University Press) 1964.

Summary Multiple sclerosis (MS) is a progressive disease of the CNS that is characterised by widespread lesions in the brain and spinal cord. MS results in motor, cognitive, and neuropsychiatric symptoms, all of which can occur independently of one another. The common cognitive symptoms include deficits in complex attention, efficiency of information processing, executive functioning, processing speed, and long-term memory. These deficits detrimentally affect many aspects of daily life, such as the ability to run a household, participate fully in society, and maintain employment—factors that can all affect the overall quality of life of the patient. The increased use of neuroimaging techniques in patients with MS has advanced our understanding of structural and functional changes in the brain that are characteristic of this disease, although much remains to be learned. Moreover, examination of efforts to treat the cognitive deficits in MS is still in the early stages.

https://www.thelancet.com/pdfs/journals/laneur/PIIS1474-4422(08)70259-X.pdf

Cognitive impairment in multiple sclerosis

Sleep and the Price of Plasticity: From Synaptic and Cellular Homeostasis to Memory Consolidation and Integration

Towards understanding the effects of individual gamification elements on intrinsic motivation and performance

Fatigue symptoms are reported by a majority of patients with multiple sclerosis (MS). Reliable assessment, however, is a demanding issue as the symptoms are experienced subjectively and as objective assessment strategies are missing. The objective of this study was to develop and validate a new tool, the Fatigue Scale for Motor and Cognitive Functions (FSMC), for the assessment of MS-related cognitive and motor fatigue. A total of 309 MS patients and 147 healthy controls were included into the validation study. The FSMC was tested against several external criteria (e.g. cognition, motivation, personality and other fatigue scales). The item-analysis and validation procedure showed that the FSMC is highly sensitive and specific in detecting fatigued MS patients, that both subscales significantly differentiated between patients and controls (p 0.91) as well as test-retest reliability (r > 0.80) were high. Cut-off values were determined to classify patients as mildly, moderately or severely fatigued. In conclusion, the FSMC is a new scale that has undergone validation based on a large sample of patients and that provides differential quantification and graduation of cognitive and motor fatigue.

The fatigue scale for motor and cognitive functions (FSMC) : validation of a new instrument to assess multiple sclerosis-related fatigue

It is heavily debated within the gamification community whether specific game elements may actually undermine users' intrinsic motivation. This online experiment examined the effects of three commonly employed game design elements -- points, leaderboard, levels -- on users' performance, intrinsic motivation, perceived autonomy and competence in an image annotation task. Implementation of these game elements significantly increased performance, but did not affect perceived autonomy, competence or intrinsic motivation. Our findings suggest that points, levels and leaderboards by themselves neither make nor break users' intrinsic motivation in non-game contexts. Instead, it is assumed that they act as progress indicators, guiding and enhancing user performance. While more research on the contextual factors that may potentially mediate the effects of game elements on intrinsic motivation is required, it seems that the implementation of points, levels, and leaderboards is a viable means to promote specific user behavior in non-game contexts.

Do points, levels and leaderboards harm intrinsic motivation?: an empirical analysis of common gamification elements

Is beautiful really usable? Toward understanding the relation between usability, aesthetics, and affect in HCI

Visual complexity is an apparent feature in website design yet its effects on cognitive and emotional processing are not well understood. The current study examined website complexity within the framework of aesthetic theory and psychophysiological research on cognition and emotion. We hypothesized that increasing the complexity of websites would have a detrimental cognitive and emotional impact on users. In a passive viewing task (PVT) 36 website screenshots differing in their degree of complexity (operationalized by JPEG file size; correlation with complexity ratings in a preliminary study r=.80) were presented to 48 participants in randomized order. Additionally, a standardized visual search task (VST) assessing reaction times, and a one-week-delayed recognition task on these websites were conducted and participants rated all websites for arousal and valence. Psychophysiological responses were assessed during the PVT and VST. Visual complexity was related to increased experienced arousal, more negative valence appraisal, decreased heart rate, and increased facial muscle tension (musculus corrugator). Visual complexity resulted in increased reaction times in the VST and decreased recognition rates. Reaction times in the VST were related to increases in heart rate and electrodermal activity. These findings demonstrate that visual complexity of websites has multiple effects on human cognition and emotion, including experienced pleasure and arousal, facial expression, autonomic nervous system activation, task performance, and memory. It should thus be considered an important factor in website design.

Klaus Opwis

Papers

Towards understanding the effects of individual gamification elements on intrinsic motivation and performance

The fatigue scale for motor and cognitive functions (FSMC) : validation of a new instrument to assess multiple sclerosis-related fatigue

Do points, levels and leaderboards harm intrinsic motivation?: an empirical analysis of common gamification elements

Is beautiful really usable? Toward understanding the relation between usability, aesthetics, and affect in HCI

Visual complexity of websites: Effects on users' experience, physiology, performance, and memory