Showing papers by "Kodiveri Muthukaliannan Gothandam published in 2010"

Preliminary screening of antimicrobial properties of few medicinal plants.

Abstract: Crude extracts were prepared from the leaves of ten medicinal plants viz., Alpinia galanga, Artabotrys uncinatus, Commelina benghalensis, Costus igneus, Euphorbia cyathopora, Justicia gendarussa, Kalanchoe pinnata, Panicum antidotale, Sauropus androgynous and Hibiscus using methanol as solvent and screened for their antibacterial activity against ten bacterial pathogens. The tested gram positive bacterial strains were Bacillus cerus, Bacillus megaterium, Micrococcus leuteus, Staphylococcus aureus, Streptococcus lactis , and gram negative strains were Pseudomonas aeruginosa, Escherichia coli, Enterobacter aerogenes, Klebsiella pneumoniae and Salmonella typhimurium . Among the ten plants tested, the methanol extracts of Alpinia galanga , Artabotrys uncinatus, Costus igneus and Yellow Hibiscus exhibited higher antibacterial activity when compared to the other plant extracts. These four plant extracts were further used for the phytochemical analysis. Results of the phytochemical analysis indicated the presence of alkaloids, phenolic compounds and flavanoids. The antibacterial activities of the leaves were due to the presence of various secondary metabolites

Increased Frequency of Down Syndrome in Young Mothers of Rural Population

Abstract: Studies were conducted in 222 children clinically diagnosed with Down syndrome (properly diagnosed on the basis of symptoms by Dr. Chandraleka, Pediatrician) to understand the frequency and type distribution of such cases; and to determine the origin of extrachromosome in the 21 st pair. Clinical diagnosis was confirmed with karyotyping. Results have shown that nondisjunction or pure trisomy 21 appears to be the main cytogenetic cause; with a percentage frequency of 96.4%; comprising of 114 boys (53.3%) and 108 girls (46.7%). Also the cytological and molecular analysis result revealed that Down syndrome was increased in the young Indian mothers especially in the rural areas. -------------------------------------------------------------------------------------------------------- 1Department of Advanced Zoology & Biotechnology, Auxillium College, Vellore 2School of Bio Sciences & Technology, VIT University, Vellore – 632014 *Corresponding author, Email: gothandam@yahoo.com Please Cite This Article As: R. Regina Mary, K.M. Gothandam, T. Lazar Mathew. 2010. Increased Frequency of Down Syndrome in Young Mothers of Rural Population. Journal of Ecobiotechnology 2/3: 40-44.