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Kotb Abdelmohsen

Researcher at National Institutes of Health

Publications -  163
Citations -  21231

Kotb Abdelmohsen is an academic researcher from National Institutes of Health. The author has contributed to research in topics: RNA-binding protein & Gene silencing. The author has an hindex of 63, co-authored 145 publications receiving 17825 citations. Previous affiliations of Kotb Abdelmohsen include Catalan Institution for Research and Advanced Studies & University of Maryland, Baltimore.

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Journal ArticleDOI

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

Daniel J. Klionsky, +2522 more
- 21 Jan 2016 - 
TL;DR: In this paper, the authors present a set of guidelines for the selection and interpretation of methods for use by investigators who aim to examine macro-autophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.
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LincRNA-p21 Suppresses Target mRNA Translation

Je Hyun Yoon, +9 more
- 24 Aug 2012 - 
TL;DR: It is proposed that HuR controls translation of a subset of target mRNAs by influencing lincRNA-p21 levels, which in turn derepressed JunB and β-catenin translation and increased the levels of these proteins.
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CircInteractome: A web tool for exploring circular RNAs and their interacting proteins and microRNAs

Dawood B. Dudekula, +5 more
- 05 Feb 2016 - 
TL;DR: A new web tool, CircInteractome (circRNA interactome), is presented, freely accessible at http://circinteractome.nia.nih.gov, for mapping RBP- and miRNA-binding sites on human circRNAs.
Journal ArticleDOI

Identification of HuR target circular RNAs uncovers suppression of PABPN1 translation by CircPABPN1.

Kotb Abdelmohsen, +10 more
- 14 Feb 2017 - 
TL;DR: It is proposed that the extensive binding of CircPABPN1 to HuR prevents HuR binding to P ABPN1 mRNA and lowers PABPN1 translation, providing the first example of competition between a circRNA and its cognate mRNA for an RBP that affects translation.
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Functional interactions among microRNAs and long noncoding RNAs

Je-Hyun Yoon, +2 more
- 01 Oct 2014 - 
TL;DR: These microRNA-lncRNA regulatory paradigms modulate gene expression patterns that drive major cellular processes which are central to mammalian physiologic and pathologic processes.