Krishna Mohan Poluri

TL;DR: It is concluded that GAG interactions and receptor activity of CXCL1 monomers and dimers are fine-tuned to regulate neutrophil trafficking for successful resolution of tissue injury.

TL;DR: The biochemical composition analysis of these microalgal cells showed apparent decline in the protein, carbohydrate and photosynthetic pigments suggesting that the arsenic intake by the cells has remodeled its cellular composition in order to cope up with the heavy metal induced stress.

TL;DR: This review throws light on the recent biomedical/biotechnological advances of GAG based biomarkers, nutraceuticals, therapeutics, and nanocomposites for inflammatory, immune disorders and their invaluable contribution in tissue engineering.

TL;DR: The structural basis of heparin binding to the murine CXCL1 dimer is characterized and it is proposed that the stability enhancement of dimers upon GAG binding regulates in vivo neutrophil trafficking by increasing the lifetime of “active” chemokines, and that this structural knowledge could be exploited for designing inhibitors that disrupt chemokine-GAG interactions and neutrophIL homing to the target tissue.

TL;DR: This review specifically aims to examine and catalog systems level data related to stress-induced TAG accumulation in oleaginous microalgae and inform future metabolic engineering strategies to develop strains with enhanced bioproductivity, which could pave a path for sustainable green energy.