K
Krishnaraj S. Rathod
Researcher at Queen Mary University of London
Publications - 105
Citations - 2518
Krishnaraj S. Rathod is an academic researcher from Queen Mary University of London. The author has contributed to research in topics: Percutaneous coronary intervention & Myocardial infarction. The author has an hindex of 22, co-authored 89 publications receiving 1736 citations. Previous affiliations of Krishnaraj S. Rathod include Barts Health NHS Trust & National Health Service.
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Journal ArticleDOI
Nitrite-Derived Nitric Oxide Protects the Rat Kidney against Ischemia/Reperfusion Injury In Vivo: Role for Xanthine Oxidoreductase
Pinpat Tripatara,Nimesh S. A. Patel,Andrew J. Webb,Krishnaraj S. Rathod,Florence Lecomte,Emanuela Mazzon,Salvatore Cuzzocrea,Mohammed M. Yaqoob,Amrita Ahluwalia,Christoph Thiemermann +9 more
TL;DR: It is demonstrated that topically administered sodium nitrite protects the rat kidney against I/R injury and dysfunction in vivo via the generation, in part, of xanthine oxidoreductase-catalyzed NO production.
Journal ArticleDOI
High Thrombus Burden in Patients With COVID-19 Presenting With ST-Segment Elevation Myocardial Infarction.
Fizzah Choudry,Stephen Hamshere,Krishnaraj S. Rathod,Mohammed M Akhtar,R. Andrew Archbold,Oliver P Guttmann,Simon Woldman,Ajay Jain,Charles Knight,Andreas Baumbach,Anthony Mathur,Daniel A. Jones +11 more
TL;DR: In patients presenting with STEMI and concurrent COVID-19 infection, there is a strong signal toward higher thrombus burden and poorer outcomes, which supports the need for establishing CO VID-19 status in all STEMI cases.
Journal ArticleDOI
Successful Recanalization of Chronic Total Occlusions Is Associated With Improved Long-Term Survival
Daniel A. Jones,Roshan Weerackody,Krishnaraj S. Rathod,Jonathan M. Behar,Sean Gallagher,Charles Knight,Charles Knight,Akhil Kapur,Ajay K. Jain,Ajay K. Jain,Martin T. Rothman,Martin T. Rothman,Craig A. Thompson,Anthony Mathur,Anthony Mathur,Andrew Wragg,Andrew Wragg,Elliot J. Smith,Elliot J. Smith +18 more
TL;DR: Successful CTO PCI is associated with improved survival out to 5 years and adoption of techniques and technologies to improve procedural success may have an impact on prognosis.
Journal ArticleDOI
Dietary nitrate improves vascular function in patients with hypercholesterolemia: a randomized, double-blind, placebo-controlled study
Shanti Velmurugan,Jasmine Ming Gan,Krishnaraj S. Rathod,Rayomand S. Khambata,Suborno M. Ghosh,Amy Hartley,Sven van Eijl,Virag Sagi-Kiss,Tahseen A Chowdhury,Michael A. Curtis,Gunter G. C. Kuhnle,William G. Wade,Amrita Ahluwalia +12 more
TL;DR: Sustained dietary nitrate ingestion improves vascular function in hypercholesterolemic patients and is associated with alterations in the oral microbiome and, in particular, nitrate-reducing genera, providing additional support for the assessment of the potential of dietary Nitrate as a preventative strategy against atherogenesis in larger cohorts.
Journal ArticleDOI
Mechanisms Underlying Erythrocyte and Endothelial Nitrite Reduction to Nitric Oxide in Hypoxia Role for Xanthine Oxidoreductase and Endothelial Nitric Oxide Synthase
Andrew J. Webb,Alexandra B. Milsom,Krishnaraj S. Rathod,Wai Lum Chu,Shehla Qureshi,Matthew J. Lovell,Florence Lecomte,David Perrett,Carmello Raimondo,Espeed Khoshbin,Zubair Ahmed,Rakesh Uppal,Nigel Benjamin,Adrian J. Hobbs,Amrita Ahluwalia +14 more
TL;DR: It is demonstrated that conversion of nitrite to NO by blood vessels and RBCs was enhanced in the presence of the Xor substrate xanthine and attenuated by the XOR inhibitor allopurinol in acidic and hypoxic conditions only.