K
Krystyna Keleman
Researcher at Howard Hughes Medical Institute
Publications - 25
Citations - 5588
Krystyna Keleman is an academic researcher from Howard Hughes Medical Institute. The author has contributed to research in topics: Mushroom bodies & Gene. The author has an hindex of 21, co-authored 23 publications receiving 5060 citations. Previous affiliations of Krystyna Keleman include Austrian Academy of Sciences & Research Institute of Molecular Pathology.
Papers
More filters
Journal ArticleDOI
A genome-wide transgenic RNAi library for conditional gene inactivation in Drosophila
Georg Dietzl,Doris Chen,Frank Schnorrer,Kuan-Chung Su,Yulia Barinova,Michaela Fellner,Michaela Fellner,Beate Gasser,Kaolin Kinsey,Kaolin Kinsey,Silvia Oppel,Silvia Oppel,Susanne Scheiblauer,Africa Couto,Vincent Marra,Krystyna Keleman,Krystyna Keleman,Barry J. Dickson,Barry J. Dickson +18 more
TL;DR: The generation and validation of a genome-wide library of Drosophila melanogaster RNAi transgenes, enabling the conditional inactivation of gene function in specific tissues of the intact organism and opening up the prospect of systematically analysing gene functions in any tissue and at any stage of the Drosophile lifespan.
Journal ArticleDOI
Trio Combines with Dock to Regulate Pak Activity during Photoreceptor Axon Pathfinding in Drosophila
Timothy P. Newsome,Susanne Schmidt,Georg Dietzl,Krystyna Keleman,Bengt Åsling,Anne Debant,Barry J. Dickson +6 more
TL;DR: It is proposed that distinct signals transduced via Trio and Dock act combinatorially to activate Pak in spatially restricted domains within the growth cone, thereby controlling the direction of axon extension.
Journal ArticleDOI
Comm Sorts Robo to Control Axon Guidance at the Drosophila Midline
Krystyna Keleman,Srikanth Rajagopalan,Diana Cleppien,David Teis,Karin Paiha,Lukas A. Huber,Gerhard M. Technau,Barry J. Dickson +7 more
TL;DR: It is shown here that comm is required in neurons, not in midline cells as previously thought, and that it is expressed specifically and transiently in commissural neurons.
Journal ArticleDOI
Short- and Long-Range Repulsion by the Drosophila Unc5 Netrin Receptor
TL;DR: The identification of the Drosophila Unc5 receptor is reported, and it is shown that it is a repulsive Netrin receptor likely to contribute to motor axon guidance, but only long-range repulsion requires Frazzled.
Journal ArticleDOI
Systematic genetic analysis of muscle morphogenesis and function in Drosophila
Frank Schnorrer,Cornelia Schönbauer,Christoph C. H. Langer,Georg Dietzl,Maria Novatchkova,Katharina Schernhuber,Michaela Fellner,Anna Azaryan,Martin Radolf,Alexander Stark,Krystyna Keleman,Barry J. Dickson +11 more
TL;DR: A role in muscle is identified for 2,785 genes, many of which are phylogenetically conserved, including genes implicated in mammalian sarcomere organization and human muscle diseases.