Kun Huang

TL;DR: It is found that RGPs progress through a coherent program in which their proliferative potential diminishes in a predictable manner, suggesting that progenitor behavior and histogenesis in the mammalian neocortex conform to a remarkably orderly and deterministic program.

TL;DR: It is shown that transient electrical coupling between radially aligned sister excitatory neurons regulates the subsequent formation of specific chemical synapses in the neocortex, suggesting a strong link between lineage-dependent transient Electrical coupling and the assembly of precise excitatories neuron microcircuits in the cortex.

TL;DR: The careful and extensive experimental results show that this new model gives more compact representations for a wide variety of natural images under a wide range of signal-to-noise ratios than many existing methods, including wavelets.

TL;DR: AD is revealed as a metabolic disease that is under tight control by JNK3, which induces a translational block by activating AMPK, thereby inhibiting the mTOR pathway and phosphorylates APP at T668, thereby facilitating its endocytosis and subsequent processing.

TL;DR: Integrative analytics approaches driven by associate research branches highlighted in this study promise to revolutionize imaging informatics as known today across the healthcare continuum for both radiology and digital pathology applications.