K
Kuniko Kusama-Eguchi
Researcher at Nihon University
Publications - 34
Citations - 751
Kuniko Kusama-Eguchi is an academic researcher from Nihon University. The author has contributed to research in topics: Spermine & Receptor. The author has an hindex of 12, co-authored 33 publications receiving 694 citations. Previous affiliations of Kuniko Kusama-Eguchi include Chiba University & Chiba Institute of Science.
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Journal ArticleDOI
Estimation of polyamine binding to macromolecules and ATP in bovine lymphocytes and rat liver.
TL;DR: Most polyamines exist as a polyamine-RNA complex in cells under the conditions that globin synthesis is stimulated by spermine in a rabbit reticulocyte cell-free system and the amount of sPermine bound to RNA was very close to the value estimated in the cells.
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Polyamine transport, accumulation, and release in brain
Takashi Masuko,Kuniko Kusama-Eguchi,Kaori Sakata,Tadashi Kusama,Shigeyuki Chaki,Shigeru Okuyama,Keith Williams,Keiko Kashiwagi,Kazuei Igarashi +8 more
TL;DR: The results suggest that the polyamine transporters present in glial cells, neurons, and synaptic vesicles each have different properties and are, presumably, different molecular entities.
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3-N-oxalyl-L-2,3-diaminopropanoic acid, a multifunctional plant metabolite of toxic reputation
TL;DR: Its presence in the drought tolerant grass pea is thought to be responsible for the crippling disease neurolathyrism, while in the longevity promoting ginseng it is named dencichine and praised for its haemostatic properties.
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Role of Caspase-12 in Amyloid β-Peptide-Induced Toxicity in Organotypic Hippocampal Slices Cultured for Long Periods
Kumiko Ishige,Noritaka Takagi,Toru Imai,Wolf-Dieter Rausch,Yasuhiro Kosuge,Tetsuroh Kihara,Kuniko Kusama-Eguchi,Hiroko Ikeda,Alexander R. Cools,John L. Waddington,Noriaki Koshikawa,Yoshihisa Ito +11 more
TL;DR: In this paper, the authors investigated Abeta-induced cell death in organotypic hippocampal slice cultures (OHCs) that were cultured for various periods in vitro, and found that OHCs cultured for relatively longer periods are more susceptible to Abeta induced toxicity and that the Abeta's induced cell death involves caspase-12-dependent pathways.
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Prostaglandin E2-induced cell death is mediated by activation of EP2 receptors in motor neuron-like NSC-34 cells.
Hiroko Miyagishi,Yasuhiro Kosuge,Yuki Yoneoka,Maiko Ozone,Manami Endo,Nobuhiro Osada,Kumiko Ishige,Kuniko Kusama-Eguchi,Yoshihisa Ito +8 more
TL;DR: Results suggest that PGE2 induces cell death by activation of EP2 in NSC-34 cells, a motor neuron-like cell line in mice.