Author
Kwang-Hyun Baek
Other affiliations: Washington State University, Seoul National University, Korea Research Institute of Bioscience and Biotechnology
Bio: Kwang-Hyun Baek is an academic researcher from Yeungnam University. The author has contributed to research in topics: Antibacterial activity & Minimum bactericidal concentration. The author has an hindex of 32, co-authored 140 publications receiving 3976 citations. Previous affiliations of Kwang-Hyun Baek include Washington State University & Seoul National University.
Papers published on a yearly basis
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TL;DR: The present review highlights various parameters affecting the synthesis of nanoparticles by green nanobiotechnology and different techniques used for characterizing the nanoparticles for their potential use in biomedical and environmental applications.
Abstract: Nanobiotechnology is gaining tremendous impetus in this era owing to its ability to modulate metals into their nanosize, which efficiently changes their chemical, physical, and optical properties. Accordingly, considerable attention is being given to the development of novel strategies for the synthesis of different kinds of nanoparticles of specific composition and size using biological sources. However, most of the currently available techniques are expensive, environmentally harmful, and inefficient with respect to materials and energy use. Several factors such as the method used for synthesis, pH, temperature, pressure, time, particle size, pore size, environment, and proximity greatly influence the quality and quantity of the synthesized nanoparticles and their characterization and applications. Additionally, characterization of the synthesized nanoparticles is essential to their potential use in various drug delivery and biomedical applications.The present review highlights various parameters affecting the synthesis of nanoparticles by green nanobiotechnology and different techniques used for characterizing the nanoparticles for their potential use in biomedical and environmental applications.
416 citations
TL;DR: The major factors affecting the production of GABA by microbial fermentation are temperature, pH, fermentation time and different media additives, therefore, these factors are summarized to provide the most up-dated information for effective GABA synthesis.
369 citations
TL;DR: It is suggested that CTEO showed a broad-spectrum of antibacterial efficacy and compromise its mode of action on membrane integrity against food-borne pathogenic bacteria.
357 citations
TL;DR: This review chiefly focused on in vivo practical utilization of plant volatile oils and components in food model-system as natural anti- Salmonella agents and provides the informative literature data on antibacterial efficacy of plant essential oils (PEOs) and their volatiles.
354 citations
TL;DR: The Vrn1-Fr1 region seemed to have a role in regulating the expression level of some of the antioxidant enzyme genes because t-APX, CAT and MnSOD expressed to significantly higher levels in the winter wheat NIL than the spring wheat Nil after 4 weeks’ cold acclimation.
250 citations
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TL;DR: An updated summary of recent advances in the field of nanomedicines and nano based drug delivery systems through comprehensive scrutiny of the discovery and application of nanomaterials in improving both the efficacy of novel and old drugs and selective diagnosis through disease marker molecules is presented.
Abstract: Nanomedicine and nano delivery systems are a relatively new but rapidly developing science where materials in the nanoscale range are employed to serve as means of diagnostic tools or to deliver therapeutic agents to specific targeted sites in a controlled manner Nanotechnology offers multiple benefits in treating chronic human diseases by site-specific, and target-oriented delivery of precise medicines Recently, there are a number of outstanding applications of the nanomedicine (chemotherapeutic agents, biological agents, immunotherapeutic agents etc) in the treatment of various diseases The current review, presents an updated summary of recent advances in the field of nanomedicines and nano based drug delivery systems through comprehensive scrutiny of the discovery and application of nanomaterials in improving both the efficacy of novel and old drugs (eg, natural products) and selective diagnosis through disease marker molecules The opportunities and challenges of nanomedicines in drug delivery from synthetic/natural sources to their clinical applications are also discussed In addition, we have included information regarding the trends and perspectives in nanomedicine area
3,112 citations
TL;DR: This work has shown how plants are able to integrate the multitude of abiotic and biotic stresses in their natural habitat into their phenotypic plasticity.
Abstract: Plants constantly face a plethora of abiotic and biotic stresses in their natural habitat. Adapting to such changes requires a great degree of phenotypic plasticity that is mainly determined by the plant's genome. We currently do not know how plants are able to integrate the multitude of partly
1,034 citations
TL;DR: The role of different antioxidants as potential selection criteria for improving plant salt tolerance has been critically discussed and the potential of this approach in counteracting stress-induced oxidative stress has been discussed at length in this review.
1,025 citations
TL;DR: The roles of a range of genes involved in salt tolerance traits are reviewed, including ion exclusion, osmotic tolerance and tissue tolerance, which are a major constraint to agriculture.
850 citations
TL;DR: An overview on the antimicrobial efficacy of combinations of EOs and their isolated components is provided, taking advantage of their synergistic and additive effects.
Abstract: Essential oils (EOs) have been long recognized for their antibacterial, antifungal, antiviral, insecticidal and antioxidant properties. They are widely used in medicine and the food industry for these purposes. The increased interest in alternative natural substances is driving the research community to find new uses and applications of these substances. EOs and their components show promising activities against many food-borne pathogens and spoilage microorganisms when tested in vitro. In food systems, higher concentrations of EOs are needed to exert similar antibacterial effects as those obtained in in vitro assays. The use of combinations of EOs and their isolated components are thus new approaches to increase the efficacy of EOs in foods, taking advantage of their synergistic and additive effects. The purpose of this review is to provide an overview on the antimicrobial efficacy of these combinations. A survey of the methods used for the determination of the interactions and mechanisms involved in the antimicrobial activities of these combinations are also reported.
840 citations