K
Kyle Tretina
Researcher at University of Maryland, Baltimore
Publications - 17
Citations - 516
Kyle Tretina is an academic researcher from University of Maryland, Baltimore. The author has contributed to research in topics: Theileria parva & Genome. The author has an hindex of 9, co-authored 15 publications receiving 340 citations. Previous affiliations of Kyle Tretina include University of Chicago & Yale University.
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Journal ArticleDOI
Interferon-induced guanylate-binding proteins: Guardians of host defense in health and disease.
Kyle Tretina,Eui-Soon Park,Eui-Soon Park,Agnieszka Maminska,Agnieszka Maminska,John D. MacMicking +5 more
TL;DR: Guanylate-binding proteins have recently emerged as central orchestrators of immunity to infection, inflammation, and neoplastic diseases, and are becoming evident for metabolic inflammatory syndromes and cancer, further underscoring the importance of GBPs within infectious as well as altered homeostatic settings.
Journal ArticleDOI
Theileria-transformed bovine leukocytes have cancer hallmarks
TL;DR: It is proposed that comparisons between cancer biology and host-Theileria interactions can reveal chemotherapeutic targets against Theileria-induced pathogenesis based on cancer treatment approaches.
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Genome-wide diversity and gene expression profiling of Babesia microti isolates identify polymorphic genes that mediate host-pathogen interactions.
Joana C. Silva,Emmanuel Cornillot,Carrie McCracken,Sahar Usmani-Brown,Ankit Dwivedi,Olukemi O. Ifeonu,Jonathan Crabtree,Hanzel T. Gotia,Azan Z. Virji,Christelle Reynes,Jacques Colinge,Vidya Prasanna Kumar,Lauren Lawres,Joseph E. Pazzi,Jozelyn Pablo,Chris Hung,Jana Brancato,Priti Kumari,Joshua Orvis,Kyle Tretina,Marcus C. Chibucos,Sandy Ott,Lisa Sadzewicz,Naomi Sengamalay,Amol C. Shetty,Qi Su,Luke J. Tallon,Claire M. Fraser,Roger Frutos,Douglas M. Molina,Peter J. Krause,Choukri Ben Mamoun +31 more
TL;DR: The genomic and immunological data presented herein provide the first insights into the determinants of B. microti interaction with its mammalian hosts and their relevance for understanding the selective pressures acting on parasite evolution.
Journal ArticleDOI
Associations between acute gastrointestinal GvHD and the baseline gut microbiota of allogeneic hematopoietic stem cell transplant recipients and donors.
C Liu,Daniel N. Frank,Matthew Horch,S Chau,Diana Ir,E A Horch,Kyle Tretina,K. van Besien,Catherine A. Lozupone,Vu H. Nguyen,Vu H. Nguyen +10 more
TL;DR: Ass associations between acute gastrointestinal GvHD (agGvHD) and 16S rRNA fecal bacterial profiles in a prospective cohort of recipients before preparative conditioning, as well as their paired HLA-matched sibling donors are examined.
Journal ArticleDOI
Discovery of a novel species, Theileria haneyi n. sp., infective to equids, highlights exceptional genomic diversity within the genus Theileria: implications for apicomplexan parasite surveillance.
Donald P. Knowles,Lowell S. Kappmeyer,Darrell Haney,David R. Herndon,Lindsay M. Fry,James B. Munro,Kelly P. Sears,Massaro W. Ueti,L.N. Wise,Marta G. Silva,David A. Schneider,Juanita F. Grause,Stephen N. White,Kyle Tretina,Richard P. Bishop,David Odongo,Angela M. Pelzel-McCluskey,Glen A. Scoles,Robert H. Mealey,Joana C. Silva +19 more
TL;DR: The extent of genome-wide sequence divergence, as well as significant morphological differences, relative to T. equi justify the classification of Theileria sp.