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Kyriacos C. Nicolaou

Researcher at Rice University

Publications -  1352
Citations -  72024

Kyriacos C. Nicolaou is an academic researcher from Rice University. The author has contributed to research in topics: Total synthesis & Ring (chemistry). The author has an hindex of 120, co-authored 1350 publications receiving 68945 citations. Previous affiliations of Kyriacos C. Nicolaou include National Institutes of Health & University of California.

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Palladium-catalyzed cross-coupling reactions in total synthesis.

TL;DR: In this Review, highlights of a number of selected syntheses are discussed, demonstrating the enormous power of these processes in the art of total synthesis and underscore their future potential in chemical synthesis.
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Cascade reactions in total synthesis.

TL;DR: The power of cascade reactions in total synthesis is illustrated in the construction of complex molecules and underscore their future potential in chemical synthesis.
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The Diels--Alder reaction in total synthesis.

TL;DR: The Diels-Alder reaction has both enabled and shaped the art and science of total synthesis over the last few decades to an extent which has yet to be eclipsed by any other transformation in the current synthetic repertoire as mentioned in this paper.
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Metathesis Reactions in Total Synthesis

TL;DR: Examples of total syntheses in which metathesis reactions of olefins, enynes, and alkynes played a crucial role and which imparted to these endeavors certain elements of novelty, elegance, and efficiency are highlighted.
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Total synthesis of taxol

TL;DR: The total synthesis of taxol is reported by a convergent strategy, which opens a chemical pathway for the production of both the natural product itself and a variety of designed taxoids.