Kyungdon Choi

TL;DR: FRoG, Fast Recalculation on GPU, enables comparative analysis of different models for estimation of physical and biological effective dose in 3D within minutes and in excellent agreement with the gold standard Monte Carlo simulation.

TL;DR: FRoG patient-specific quality assurance (QA) has been performed and matched the measured QA dosimetric data within ~2.0% for both particle species, demonstrating FRoG’s potential to bolster clinical activity with proton and carbon ion beams at CNAO.

TL;DR: CF/PEEK spinal fixation devices resulted dosimetrically more suitable than commonly-used Ti implants for post-operative PT, leading to a lower degree of dose degradation in case of contouring and/or set-up uncertainties.

TL;DR: This pre-clinical trial landmarks the first measurements taken in anthropomorphic settings for helium, carbon and oxygen ion-beam therapy, and demonstrates satisfactory agreement with gold standard Monte Carlo simulation and measurement, superior to the commercial system.

TL;DR: This work aims to update the local effect model (LEM)-based constraints for the rectum using microdosimetric kinetic model (mMKM)-defined values, relying on RBE translation and the analysis of long-term clinical outcomes.