L
L. Harivardhan Reddy
Researcher at University of Paris-Sud
Publications - 26
Citations - 4024
L. Harivardhan Reddy is an academic researcher from University of Paris-Sud. The author has contributed to research in topics: Gemcitabine & Nucleoside analogue. The author has an hindex of 24, co-authored 26 publications receiving 3622 citations. Previous affiliations of L. Harivardhan Reddy include University of Turin & University of Granada.
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Journal ArticleDOI
Magnetic nanoparticles: design and characterization, toxicity and biocompatibility, pharmaceutical and biomedical applications.
TL;DR: Biocompatibility, Pharmaceutical and Biomedical Applications L. Harivardhan Reddy,‡ Jose ́ L. Arias, Julien Nicolas,† and Patrick Couvreur*,†.
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Squalene: A natural triterpene for use in disease management and therapy.
TL;DR: This paper is the first review of its kind and offers greater insight into squalene's direct or indirect contribution to disease management and therapy.
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Squalenoyl nanomedicines as potential therapeutics.
Patrick Couvreur,Barbara Stella,L. Harivardhan Reddy,Hervé Hillaireau,Catherine Dubernet,Didier Desmaële,Sinda Lepetre-Mouelhi,Flavio Rocco,Nathalie Dereuddre-Bosquet,Pascal Clayette,Véronique Rosilio,Véronique Marsaud,Jack-Michel Renoir,Luigi Cattel +13 more
TL;DR: The squalenoylation of gemcitabine and other antiretroviral nucleosides led to more potent drugs when tested in primary cultures of HIV-infected lymphocytes and in vivo in experimental leukemia both after intravenous and oral administration.
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A unique squalenoylated and nonpegylated doxorubicin nanomedicine with systemic long-circulating properties and anticancer activity
Andrei Maksimenko,Franco Dosio,Julie Mougin,Annalisa Ferrero,Séverine Wack,L. Harivardhan Reddy,Andree Anne Weyn,Elise Lepeltier,Claudie Bourgaux,Barbara Stella,Luigi Cattel,Patrick Couvreur +11 more
TL;DR: SQ-Dox nanoassembly-treated MiaPaCa-2 pancreatic tumor xenografts in mice decreased by 95% compared with the tumors in the saline-treated mice, which was significantly higher than the 29% reduction achieved by native doxorubicin.
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Squalene Based Nanocomposites: A New Platform for the Design of Multifunctional Pharmaceutical Theragnostics
José L. Arias,L. Harivardhan Reddy,Mohammad Othman,Brigitte Gillet,Didier Desmaële,Fatima Zouhiri,Franco Dosio,Ruxandra Gref,Patrick Couvreur +8 more
TL;DR: By combining different anticancer medicines as well as contrast imaging agents in NPs, the design of a novel theragnostic nanomedicine is reported which opens the door toward generic conceptual framework for cancer treatment and diagnosis.