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L M Zir

Bio: L M Zir is an academic researcher. The author has contributed to research in topics: Cardiac catheterization & Pulmonic stenosis. The author has an hindex of 1, co-authored 1 publications receiving 12 citations.

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TL;DR: A 52-year-old man is described with TAPVC and severe calcific pulmonic stenosis, a rare cardiac congenital abnormality which usually results in death in infancy or early childhood.
Abstract: Total anomalous pulmonary venous connection (TAPVC) is a rare cardiac congenital abnormality which usually results in death in infancy or early childhood. We describe a 52-year-old man with TAPVC and severe calcific pulmonic stenosis. Both diagnoses were suspected clinically and from the chest X-ray. Cardiac catheterization was confirmatory, and the patient underwent surgery. His initial postoperative course has been unremarkable. The hemodynamic factors relevant to long survival and relative freedom from symptoms in TAPVC are considered based on findings in this patient.

14 citations


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Journal ArticleDOI
22 Mar 1971-JAMA
TL;DR: By emphasizing deductive reasoning and minimizing rote learning, Dr. Perloff reveals a sentient physician, rather than a diagnosis machine, which maximizes the usefulness of clinical data and their correlation with ordinary x-ray films and electrocardiograms, as well as with pathologic physiology.
Abstract: Diagnostic approaches to many congenital abnormalities deal with complexities which may daunt all but those in daily contact with this rewarding branch of cardiology. This has been due to the possible permutations and combinations involving dislocated, absent, or flawed chambers, vessels, and valves, not to mention shunts in one or both directions. Recently, increasingly sophisticated diagnostic procedures superficially appear to have narrowed the clinician's scope. Actually, the converse is true, as demonstrated by this complete book, which, on every well-written page, justifies the words "clinical recognition" of the title. Chapters progress logically from anatomy through clinical manifestations. By emphasizing deductive reasoning and minimizing rote learning, Dr. Perloff reveals a sentient physician, rather than a diagnosis machine. This approach maximizes the usefulness of clinical data and their correlation with ordinary x-ray films and electrocardiograms, as well as with pathologic physiology. Relatively pure forms of each disorder are stressed, and the composite

107 citations

Journal ArticleDOI
TL;DR: Vascular lesions must be considered in the differential diagnosis of mediastinal masses and angiography is used most often, but radionuclide flow studies and computed tomographic scanning may also be useful.

32 citations

Journal Article
TL;DR: In this paper, it was shown that the cardiovascular contour provided a distinctive radiological sign of total pulmonary venous drainage through a persistent left superior vena cava into the left innominate vein.
Abstract: When Parsons et al. (1952) reported two patients with total pulmonary venous drainage into the right heart through a persistent left superior vena cava and the left innominate vein they were able to find accounts of only nine other patients, six of whom were babies diagnosed at autopsy. Another, although only diagnosed in life as having abnormal pulmonary venous drainage into the right superior vena cava by Johnson and McRae (1948), had a teleradiogram similar to those now thought to be characteristic of total pulmonary venous drainage through a persistent left superior vena cava. Two others, reported by Friedlich et al. (1950), were the first patients with this congenital anomaly fully diagnosed in life. Adding Taussig's (1947) Case 33, the four patients of Snellen and Albers (1952), and the three patients of Gardner and Oram (1953) the number of published cases is nineteen. From these records it is apparent that before the advent of angiocardiography and cardiac catheterization this congenital anomaly was recognized only at autopsy. Following the introduction of these special methods of investigation it was possible to diagnose the anomaly in life and to recognize it more frequently. The patients reported by Taussig (1947), Parsons et al. (1952), Snellen and Albers (1952), and Gardner and Oram (1953) have similar teleradiograms in which the striking feature is a \" cottageloaf\" shaped cardiovascular shadow, formed by an ovoid upper mediastinal mass and an enlarged heart. The two latter groups of observers demonstrated by angiocardiography that the ovoid mediastinal enlargement is produced on the left by a persistent left superior vena cava and on the right by the dilated right superior vena cava, and they supported Taussig's (1947) suggestion that the cardiovascular contour provides a distinctive radiological sign of total pulmonary venous drainage through a left superior vena cava into the left innominate vein. Brown (1950), who was already aware of the radiological appearance of a persistent left superior vena cava, independently recognized the significance of these distinctive radiological features and diagnosed this anomaly on six occasions at routine clinical and radiological examination of patients in cardiac clinics in Hull and in the Sheffield Region. Three patients (Cases 4, 5, and 6) were already under observation but the others (Cases 1, 2, and 3) were seen for the first time early in 1953, which suggests that this anomaly is not so rare as the published cases indicate. When it is widely known that the radiological features are sufficiently characteristic to allow the anomaly to be recognized at routine examination there will probably be an increase in the frequency of its diagnosis similar to that following the introduction of the special methods of investigation.

21 citations

Journal ArticleDOI
TL;DR: The importance of considering vascular entities in the differential diagnosis of mediastinal masses is stressed, as it is seen that vascular lesions of the mediastinum can be mistaken for, or misinterpreted as, one of these more common mediastinals.

13 citations