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Laura D. Attardi

Researcher at Stanford University

Publications -  132
Citations -  21883

Laura D. Attardi is an academic researcher from Stanford University. The author has contributed to research in topics: Cancer & Gene. The author has an hindex of 50, co-authored 124 publications receiving 19589 citations. Previous affiliations of Laura D. Attardi include University of California, Berkeley & Texas Medical Center.

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Journal ArticleDOI

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

Daniel J. Klionsky, +2522 more
- 21 Jan 2016 - 
TL;DR: In this paper, the authors present a set of guidelines for the selection and interpretation of methods for use by investigators who aim to examine macro-autophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.
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A Large Intergenic Noncoding RNA Induced by p53 Mediates Global Gene Repression in the p53 Response

Maite Huarte, +21 more
- 06 Aug 2010 - 
TL;DR: A model whereby transcription factors activate lincRNAs that serve as key repressors by physically associating with repressive complexes and modulate their localization to sets of previously active genes is proposed.

A Large Intergenic Noncoding RNA Induced by p53 Mediates Global Gene Repression in the p53 Response

Maite Huarte, +21 more
TL;DR: In this paper, the identification of lincRNAs (lincRNA-p21) that serve as a repressor in p53-dependent transcriptional responses was reported, and the observed transcriptional repression was mediated through the physical association with hnRNP-K at repressed genes and regulation of p53 mediates apoptosis.
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Unravelling mechanisms of p53-mediated tumour suppression

Kathryn T. Bieging, +2 more
- 17 Apr 2014 - 
TL;DR: The roles of classical p53 functions, as well as emerging p53-regulated processes, in tumour suppression are discussed.
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The role of apoptosis in cancer development and treatment response.

J. Martin Brown, +1 more
- 01 Mar 2005 - 
TL;DR: This work has shown that in many tumours, apoptosis is not the main mechanism for the death of cancer cells in response to common treatment regimens, suggesting that other modes of cell death are involved in the response to therapy.