Lauren P. Deflores

TL;DR: Overall, this study shows that interferometeric quantitative phase microscopy represents a noninvasive optical assay for monitoring cell growth, characterizing cellular motility, and investigating the subcellular motions of living cells.

TL;DR: By use of the Fourier decomposition of a low-coherence optical image field into two spatial components that can be controllably shifted in phase with respect to each other, a new high-transverse-resolution quantitative-phase microscope has been developed.

TL;DR: Two-dimensional infrared (2D IR) spectroscopy of the amide I protein backbone vibration is reviewed to report on solvent accessibility and structural stability in proteins, and Multimode 2D IR spectroscopic has been used to correlate the structure sensitivity of amid I with amide II to reports on solvent accessible and structural Stability in proteins.

TL;DR: Good quantitative agreement is found between the experimentally retrieved and simulated correlation functions over all time scales when the solute-solvent interactions are determined from the electrostatic potential between the solvent and the atomic sites of the amide group.

TL;DR: To demonstrate the ability of this method to capture molecular dynamics, couplings and structure found in the conventional boxcar 2D FT spectroscopy, a series of 2D spectra of a metal carbonyl, and a beta-sheet protein are acquired.