L
Laurens G. Wilming
Researcher at University of Massachusetts Amherst
Publications - 4
Citations - 3162
Laurens G. Wilming is an academic researcher from University of Massachusetts Amherst. The author has contributed to research in topics: Extracellular matrix & Osteoblast. The author has an hindex of 4, co-authored 4 publications receiving 3115 citations.
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Journal ArticleDOI
Progressive development of the rat osteoblast phenotype in vitro: Reciprocal relationships in expression of genes associated with osteoblast proliferation and differentiation during formation of the bone extracellular matrix
Thomas A. Owen,Michael A. Aronow,Victoria Shalhoub,Leesa M. Barone,Laurens G. Wilming,Melissa S. Tassinari,Mary Beth Kennedy,Shirwin M. Pockwinse,Jane B. Lian,Gary S. Stein +9 more
TL;DR: The relationship of cell proliferation to the temporal expression of genes characterizing a developmental sequence associated with bone cell differentiation was examined in primary diploid cultures of fetal calvarial derived osteoblasts by the combined use of autoradiography, histochemistry, biochemistry, and mRNA assays of osteoblast cell growth and phenotypic genes.
Progressive Development of the Rat Osteoblast Phenotype In Vitro: Reciprocal Relationships in Expression of Genes Associated With Osteoblast Proliferation and Differentiation During Formation of the
Thomas A. Owen,Michael A. Aronow,Victoria Shalhoub,Leesa M. Barone,Laurens G. Wilming,Melissa S. Tassinari,Mary Beth Kennedy,Jane B. Lian,Gary S. Stein +8 more
TL;DR: In this article, the relationship of cell proliferation to the temporal expression of genes characterizing a developmental sequence associated with bone cell differentiation was examined in primary diploid cultures of fetal calvarial derived osteoblasts by the combined use of autoradiography, histochemistry, biochemistry, and mRNA assays of osteoblast cell growth and phenotypic genes.
Journal ArticleDOI
Expression of cell growth and bone specific genes at single cell resolution during development of bone tissue-like organization in primary osteoblast cultures.
TL;DR: In situ analyses of gene expression during osteoblast growth and differentiation at the single cell level establish that a population of proliferating calvarial‐derived cells subsequently expresses osteopontin and osteocalcin in cells developing into multilayered nodules with a tissue‐like organization.
Journal ArticleDOI
Differential association of membrane-bound and non-membrane-bound polysomes with the cytoskeleton.
Gerard Zambetti,Laurens G. Wilming,Edward G. Fey,Sheldon Penman,Janet L. Stein,Gary S. Stein +5 more
TL;DR: In this article, the authors reported a differential release of specific mRNAs from the cytoskeleton by cytochalasin D treatment, such as histone mRNA and c-fos mRNA.