L
Lee Edwards
Researcher at GlaxoSmithKline
Publications - 107
Citations - 2064
Lee Edwards is an academic researcher from GlaxoSmithKline. The author has contributed to research in topics: Epithelial sodium channel & Cystic fibrosis. The author has an hindex of 25, co-authored 102 publications receiving 1673 citations. Previous affiliations of Lee Edwards include University of Manchester & University of Hertfordshire.
Papers
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Journal ArticleDOI
Batch versus Flow Photochemistry: A Revealing Comparison of Yield and Productivity
Luke D. Elliott,Jonathan P. Knowles,Paul J. Koovits,Katie G. Maskill,Michael J. Ralph,Guillaume Lejeune,Lee Edwards,Richard I. Robinson,Ian Clemens,Brian Cox,David D. Pascoe,Guido Koch,Martin Eberle,Malcolm B. Berry,Kevin I. Booker-Milburn +14 more
TL;DR: A broad range of synthetic photochemical transformations were optimized in both reactor modes and their yields and productivities compared and it was revealed that the productivity of flow reactors varied very little to that of their batch counterparts when the key reaction parameters were matched.
Journal ArticleDOI
Defining the ‘object’ of public relations research: A new starting point:
TL;DR: In this article, the importance of paradigmatic variety in the scholarly field of public relations is considered and the role of conflict and cooperation between different paradigms play in the development of academic fields.
Journal ArticleDOI
Photons as a 21st century reagent.
Holly E. Bonfield,Thomas Knauber,François Lévesque,Eric G. Moschetta,Flavien Susanne,Lee Edwards +5 more
TL;DR: A pharmaceutical industry viewpoint on how the fundamental laws of photochemistry are used to identify the parameters required to implement photochemistry from lab to scale is presented.
Journal ArticleDOI
Naphthalen -1 -yl -(4 -pentyloxynaphthalen -1 -yl)methanone : A potent, orally bioavailable human CB1/CB2 dual agonist with antihyperalgesic properties and restricted central nervous system penetration
Edward K. Dziadulewicz,Stuart Bevan,Christopher Thomas Brain,Paul R. Coote,Andrew James Culshaw,Andrew J. Davis,Lee Edwards,Adrian J. Fisher,Alyson Fox,Clive Gentry,Alex Groarke,Hart Terance William,Werner Huber,Iain F. James,Adam Kesingland,Luigi La Vecchia,Yvonne Loong,Isabelle Lyothier,Kara McNair,† Cathal O'Farrell,Marcus Peacock,Portmann Robert,Ulrich Schopfer,and Mohammed Yaqoob,Jiri Zadrobilek +24 more
TL;DR: A new class of cannabinoid ligands was rationally designed from known aminoalkylindole agonists and showed good binding and functional activities at human CB1 and CB2 receptors, which led to the discovery of a novel CB1/CB2 dual agonist, naphthalen-1-yl-(4-pentyloxynaphthalanone), which displays good oral bioavailability, potent antihyperalgesic activity in animal models, and limited brain penetration.
BookDOI
Public relations, society and culture : theoretical and empirical explorations
Lee Edwards,Caroline E.M. Hodges +1 more
TL;DR: In this article, the authors discuss the implications of a socio-cultural 'turn' in public relations scholarship Lee Edwards, Manchester Business School (University of Manchester) and Caroline E. M. Hodges, Bournemouth University.