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Lei Lei

Researcher at Peking Union Medical College

Publications -  9
Citations -  381

Lei Lei is an academic researcher from Peking Union Medical College. The author has contributed to research in topics: Colonoscopy & Renal function. The author has an hindex of 4, co-authored 7 publications receiving 189 citations. Previous affiliations of Lei Lei include Sichuan University.

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Effect of a deep-learning computer-aided detection system on adenoma detection during colonoscopy (CADe-DB trial): a double-blind randomised study.

TL;DR: The effectiveness of a CADe system that avoids potential operational bias during colonoscopy is assessed in a double-blind randomised trial at the endoscopy centre in Caotang branch hospital of Sichuan Provincial People's Hospital in China.
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Value of urinary KIM-1 and NGAL combined with serum Cys C for predicting acute kidney injury secondary to decompensated cirrhosis.

TL;DR: Urinary KIM-1, urinary NGAL, serum Cys C, and the combined detection factor, as screening indices, could aid in the early diagnosis of AKI secondary to decompensated cirrhosis.
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Down-regulation of microRNA-375 regulates adipokines and inhibits inflammatory cytokines by targeting AdipoR2 in non-alcoholic fatty liver disease.

TL;DR: Investigation of the regulatory role of miR‐375 in the molecular mechanisms of the pathogenic progression of NAFLD finds that it was increased in the serum of high fat diet (HFD)‐feeding mice comparing to that in healthy controls, and found that Adiponectin receptor 2 was a target of mi R‐375 by binding directly to the 3′UTR of it.
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Overexpression of miR-142-5p inhibits the progression of nonalcoholic steatohepatitis by targeting TSLP and inhibiting JAK-STAT signaling pathway.

TL;DR: Overexpression of TSLP and JAK-STAT signaling pathway activation could reverse the effects of miR-142-5p on NASH, which might be a novel latent target for NASH therapy.