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Lei Wang

Bio: Lei Wang is an academic researcher from Chinese Academy of Sciences. The author has contributed to research in topics: Precipitation & Medicine. The author has an hindex of 50, co-authored 429 publications receiving 9543 citations. Previous affiliations of Lei Wang include Taizhou University & Peking University.


Papers
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Journal ArticleDOI
TL;DR: This method has been successfully applied to determine Cu(2+) in real water samples and shows good results in terms of particle size and quantum yield.
Abstract: Dr. S. Liu , J. Tian , L. Wang , Zhang , Dr. . Y X. Qin , Luo , . Y Prof. X. Sun State Key Lab of Electroanalytical Chemistry Changchun Institute of Applied Chemistry Changchun 130022, Jilin, China; Fax: ( + 86) 431-85262065 E-mail: sunxp@ciac.jl.cn J. Tian Graduate School of the Chinese Academy of Sciences Beijing 100039, China Prof. A. M. Asiri , A. O. Al-Youbi , Prof. X. Sun Chemistry Department, Faculty of Science King Abdulaziz University Jeddah 21589, Saudi Arabia Prof. A. M. Asiri , A. O. Al-Youbi , Prof. X. Sun Center of Excellence for Advanced Materials ResearchKing Abdulaziz University Jeddah 21589, Saudi Arabia

1,295 citations

Journal ArticleDOI
TL;DR: In this paper , the authors show that BA.4/BA.5 exhibit higher transmissibility than BA.2.1, BA.12.1 and BA.1.
Abstract: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron sublineages BA.2.12.1, BA.4 and BA.5 exhibit higher transmissibility than the BA.2 lineage1. The receptor binding and immune-evasion capability of these recently emerged variants require immediate investigation. Here, coupled with structural comparisons of the spike proteins, we show that BA.2.12.1, BA.4 and BA.5 (BA.4 and BA.5 are hereafter referred collectively to as BA.4/BA.5) exhibit similar binding affinities to BA.2 for the angiotensin-converting enzyme 2 (ACE2) receptor. Of note, BA.2.12.1 and BA.4/BA.5 display increased evasion of neutralizing antibodies compared with BA.2 against plasma from triple-vaccinated individuals or from individuals who developed a BA.1 infection after vaccination. To delineate the underlying antibody-evasion mechanism, we determined the escape mutation profiles2, epitope distribution3 and Omicron-neutralization efficiency of 1,640 neutralizing antibodies directed against the receptor-binding domain of the viral spike protein, including 614 antibodies isolated from people who had recovered from BA.1 infection. BA.1 infection after vaccination predominantly recalls humoral immune memory directed against ancestral (hereafter referred to as wild-type (WT)) SARS-CoV-2 spike protein. The resulting elicited antibodies could neutralize both WT SARS-CoV-2 and BA.1 and are enriched on epitopes on spike that do not bind ACE2. However, most of these cross-reactive neutralizing antibodies are evaded by spike mutants L452Q, L452R and F486V. BA.1 infection can also induce new clones of BA.1-specific antibodies that potently neutralize BA.1. Nevertheless, these neutralizing antibodies are largely evaded by BA.2 and BA.4/BA.5 owing to D405N and F486V mutations, and react weakly to pre-Omicron variants, exhibiting narrow neutralization breadths. The therapeutic neutralizing antibodies bebtelovimab4 and cilgavimab5 can effectively neutralize BA.2.12.1 and BA.4/BA.5, whereas the S371F, D405N and R408S mutations undermine most broadly sarbecovirus-neutralizing antibodies. Together, our results indicate that Omicron may evolve mutations to evade the humoral immunity elicited by BA.1 infection, suggesting that BA.1-derived vaccine boosters may not achieve broad-spectrum protection against new Omicron variants.

740 citations

Journal ArticleDOI
Antonio Terracciano1, Ahmed M. Abdel-Khalek, N. Ádám2, L. Adamovová3, C.-k. Ahn4, H.-n. Ahn4, B. M. Alansari, Lidia Alcalay5, Jüri Allik6, Alois Angleitner, María Dolores Avia7, Lindsay E. Ayearst8, Claudio Barbaranelli9, Andrew Beer10, M. A. Borg-Cunen11, Denis Bratko, Marina Brunner-Sciarra12, L. Budzinski13, N. Camart14, Donatien Dahourou15, F. De Fruyt, M. I. P. de Lima16, G. E. H. del Pilar17, Ed Diener18, Ruth Falzon11, K. Fernando19, Emília Ficková3, Ronald Fischer20, Carmen Flores-Mendoza, M. A. Ghayur21, Sami Gülgöz22, Bo Hagberg23, Jamin Halberstadt19, Magdalena S. Halim24, Martina Hřebíčková25, J. Humrichouse10, Hans Henrik Jensen26, D. D. Jocic, F. H. Jónsson27, Brigitte Khoury28, W. Klinkosz24, Goran Knežević29, Mary Anne Lauri11, N. Leibovich30, Thomas A. Martin31, Iris Marušić, Khairul Anwar Mastor32, David Matsumoto33, Margaret McRorie34, B. Meshcheriakov35, Erik Lykke Mortensen26, M. Munyae36, János Nagy2, Katsuharu Nakazato37, Florence Nansubuga38, Shigehiro Oishi39, A. O. Ojedokun40, Fritz Ostendorf, Delroy L. Paulhus41, S. Pelevin35, J.-M. Petot14, N. Podobnik, Jose Porrata42, V. S. Pramila43, G. Prentice34, Anu Realo6, Norma Reátegui12, Jean-Pierre Rolland14, Jérôme Rossier44, Willibald Ruch, Velko S. Rus45, M.L. Sánchez-Bernardos7, Vanina Schmidt30, S. Sciculna-Calleja11, A. Sekowski24, Jane Shakespeare-Finch46, Yoshiko Shimonaka47, Franco Simonetti5, Tilahun Sineshaw48, Jerzy Siuta49, Peter B. Smith50, Paul D. Trapnell51, K. K. Trobst8, Lei Wang52, Michelle Yik53, A. Zupančič, Robert R. McCrae1 
National Institutes of Health1, Eötvös Loránd University2, Slovak Academy of Sciences3, Pusan National University4, Pontifical Catholic University of Chile5, University of Tartu6, Complutense University of Madrid7, Keele University8, Sapienza University of Rome9, University of Iowa10, University of Malta11, Cayetano Heredia University12, University of Melbourne13, University of Paris14, University of Ouagadougou15, University of Coimbra16, University of the Philippines Diliman17, University of Illinois at Urbana–Champaign18, University of Otago19, Victoria University of Wellington20, Al Akhawayn University21, Koç University22, Lund University23, The Catholic University of America24, Academy of Sciences of the Czech Republic25, University of Copenhagen26, University of Iceland27, American University of Beirut28, University of Belgrade29, University of Buenos Aires30, Susquehanna University31, National University of Malaysia32, San Francisco State University33, Queen's University Belfast34, International University, Cambodia35, University of Botswana36, Iwate Prefectural University37, Makerere University38, University of Virginia39, University of Ibadan40, University of British Columbia41, University of Puerto Rico, Río Piedras42, Andhra University43, University of Lausanne44, University of Ljubljana45, Queensland University of Technology46, Bunkyo Gakuin University47, Ramapo College48, Jagiellonian University49, University of Sussex50, University of Winnipeg51, Peking University52, Hong Kong University of Science and Technology53
07 Oct 2005-Science
TL;DR: Perceptions of national character appear to be unfounded stereotypes that may serve the function of maintaining a national identity.
Abstract: Most people hold beliefs about personality characteristics typical of members of their own and others' cultures. These perceptions of national character may be generalizations from personal experience, stereotypes with a "kernel of truth," or inaccurate stereotypes. We obtained national character ratings of 3989 people from 49 cultures and compared them with the average personality scores of culture members assessed by observer ratings and self-reports. National character ratings were reliable but did not converge with assessed traits. Perceptions of national character thus appear to be unfounded stereotypes that may serve the function of maintaining a national identity.

403 citations

Journal ArticleDOI
TL;DR: The authors found that cross-cultural variations in aging perceptions were associated with culture-level indicators of population aging, education levels, values, and national character stereotypes, and these associations were stronger for societal views on aging and perceptions of socioemotional changes than for perceptions of physical and cognitive changes.
Abstract: College students (N=3,435) in 26 cultures reported their perceptions of age-related changes in physical, cognitive, and socioemotional areas of functioning and rated societal views of aging within their culture. There was widespread cross-cultural consensus regarding the expected direction of aging trajectories with (a) perceived declines in societal views of aging, physical attractiveness, the ability to perform everyday tasks, and new learning; (b) perceived increases in wisdom, knowledge, and received respect; and (c) perceived stability in family authority and life satisfaction. Cross-cultural variations in aging perceptions were associated with culture-level indicators of population aging, education levels, values, and national character stereotypes. These associations were stronger for societal views on aging and perceptions of socioemotional changes than for perceptions of physical and cognitive changes. A consideration of culture-level variables also suggested that previously reported differences in aging perceptions between Asian and Western countries may be related to differences in population structure.

363 citations

Journal ArticleDOI
TL;DR: The authors present the results of four studies that examined cultural differences in reasoning about psychological contradiction and the effects of naive dialecticism on self-evaluations and psychological adjustment and found that increased dialecticism was related to decreased psychological adjustment.
Abstract: A well-documented finding in the literature is that members of many East Asian cultures report lower self-esteem and psychological well-being than do members of Western cultures. The authors present the results of four studies that examined cultural differences in reasoning about psychological contradiction and the effects of naive dialecticism on self-evaluations and psychological adjustment. Mainland Chinese and Asian Americans exhibited greater "ambivalence" or evaluative contradiction in their self-attitudes than did Western synthesis-oriented cultures on a traditional self-report measure of self-esteem (Study 1) and in their spontaneous self-descriptions (Study 2). Naive dialecticism, as assessed with the Dialectical Self Scale, mediated the observed cultural differences in self-esteem and well-being (Study 3). In Study 4, the authors primed naive dialecticism and found that increased dialecticism was related to decreased psychological adjustment. Implications for the conceptualization and measurement of self-esteem and psychological well-being across cultures are discussed.

309 citations


Cited by
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5,680 citations

Journal Article
TL;DR: In this article, the authors present a document, redatto, voted and pubblicato by the Ipcc -Comitato intergovernativo sui cambiamenti climatici - illustra la sintesi delle ricerche svolte su questo tema rilevante.
Abstract: Cause, conseguenze e strategie di mitigazione Proponiamo il primo di una serie di articoli in cui affronteremo l’attuale problema dei mutamenti climatici. Presentiamo il documento redatto, votato e pubblicato dall’Ipcc - Comitato intergovernativo sui cambiamenti climatici - che illustra la sintesi delle ricerche svolte su questo tema rilevante.

4,187 citations

01 Jan 1989
TL;DR: In this article, a two-dimensional version of the Pennsylvania State University mesoscale model has been applied to Winter Monsoon Experiment data in order to simulate the diurnally occurring convection observed over the South China Sea.
Abstract: Abstract A two-dimensional version of the Pennsylvania State University mesoscale model has been applied to Winter Monsoon Experiment data in order to simulate the diurnally occurring convection observed over the South China Sea. The domain includes a representation of part of Borneo as well as the sea so that the model can simulate the initiation of convection. Also included in the model are parameterizations of mesoscale ice phase and moisture processes and longwave and shortwave radiation with a diurnal cycle. This allows use of the model to test the relative importance of various heating mechanisms to the stratiform cloud deck, which typically occupies several hundred kilometers of the domain. Frank and Cohen's cumulus parameterization scheme is employed to represent vital unresolved vertical transports in the convective area. The major conclusions are: Ice phase processes are important in determining the level of maximum large-scale heating and vertical motion because there is a strong anvil componen...

3,813 citations

Journal ArticleDOI
TL;DR: The progress in the research and development of CQDs is reviewed with an emphasis on their synthesis, functionalization and technical applications along with some discussion on challenges and perspectives in this exciting and promising field.
Abstract: Fluorescent carbon nanoparticles or carbon quantum dots (CQDs) are a new class of carbon nanomaterials that have emerged recently and have garnered much interest as potential competitors to conventional semiconductor quantum dots. In addition to their comparable optical properties, CQDs have the desired advantages of low toxicity, environmental friendliness low cost and simple synthetic routes. Moreover, surface passivation and functionalization of CQDs allow for the control of their physicochemical properties. Since their discovery, CQDs have found many applications in the fields of chemical sensing, biosensing, bioimaging, nanomedicine, photocatalysis and electrocatalysis. This article reviews the progress in the research and development of CQDs with an emphasis on their synthesis, functionalization and technical applications along with some discussion on challenges and perspectives in this exciting and promising field.

3,514 citations