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Lei Wang

Bio: Lei Wang is an academic researcher from Chinese Academy of Sciences. The author has contributed to research in topics: Precipitation & Medicine. The author has an hindex of 50, co-authored 429 publications receiving 9543 citations. Previous affiliations of Lei Wang include Taizhou University & Peking University.


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TL;DR: In this paper, Li et al. showed that surface modification of cathode materials can enhance the cycle stability of LiNi 1 3 Co 1/3 Mn 1 /3 O 2.

23 citations

Posted ContentDOI
TL;DR: Based on the first-order radiative transfer model calculation, a unique method for estimating surface soil moisture over the study area is developed in this article, which can contribute to better understand the climate change and forecast modeling for this area.
Abstract: . In this paper, 7 years (during the growing season (April–October) of 2002–2008) of the Advanced Microwave Scanning Radiometer (AMSR-E) data taken at a frequency of 6.9 GHz for night observations at both polarizations are processed and used to conduct 7 years of surface soil moisture dataset for an arid area, in Northwestern China. This soil moisture dataset can contribute to better understanding the climate change and forecast modeling for this area. Based on the first-order radiative transfer model calculation, a unique method for estimating surface soil moisture over the study area is developed. Considering extremely complex topography over the study area, we have to present a parameterization of surface roughness at the 6.9 GHz and spatial resolution of the AMSR-E using the annual minimum MPDI (Microwave Polarization Difference Index). For validation purpose, the comparisons of soil moisture patterns with precipitation fields are made. The results indicate the evolutions of soil moisture estimated from the AMSR-E and antecedent ground daily precipitations are in a good agreement. Furthermore, a series of rainfall traces is captured over the Taklimakan Desert. Comparisons of the estimated values of soil moisture with the ground observations are also made for two reprehensive sites over 2002–2004. The results indicate there has a good agreement between them, with higher correlation coefficients (R=0.649, 0.604) and RMSE (3.5, 5.4%), and the soil moisture product derived from the AMSR-E is realistic and acceptable. This new long time series of estimated soil moisture will prove valuable for other studies of climate change and model evaluation.

23 citations

Journal ArticleDOI
TL;DR: In this article, a human monoclonal antibody, HB27, was developed to prevent SARS-CoV-2 attachment to its cellular receptor at sub-nM concentrations.
Abstract: Receptor recognition and subsequent membrane fusion are essential for the establishment of successful infection by SARS-CoV-2. Halting these steps can cure COVID-19. Here we have identified and characterized a potent human monoclonal antibody, HB27, that blocks SARS-CoV-2 attachment to its cellular receptor at sub-nM concentrations. Remarkably, HB27 can also prevent SARS-CoV-2 membrane fusion. Consequently, a single dose of HB27 conferred effective protection against SARS-CoV-2 in two established mouse models. Rhesus macaques showed no obvious adverse events when administrated with 10 times the effective dose of HB27. Cryo-EM studies on complex of SARS-CoV-2 trimeric S with HB27 Fab reveal that three Fab fragments work synergistically to occlude SARS-CoV-2 from binding to the ACE2 receptor. Binding of the antibody also restrains any further conformational changes of the receptor binding domain, possibly interfering with progression from the prefusion to the postfusion stage. These results suggest that HB27 is a promising candidate for immuno-therapies against COVID-19.

23 citations

Journal ArticleDOI
Zhe Shang1, Lei Wang1, Han Wu1
TL;DR: The findings suggest that the ownership effect could be reversed by conscientiousness induced by perceived Choosership in the agency relationship, while the choosership effect is attenuated and even disappears under the influence of perceived ownership.
Abstract: The present research examined the influence of perceived ownership (self/other) and perceived chooser (self/other) of stocks on brain activity, and investigated whether differential brain responses to stock outcomes as a result of perceived differences in ownership of stock would be modulated by perceived chooser of stock. We used a 2 (stock chooser: self, other) × 2 (stock owner: self, other) within-subject design to represent four types of chooser-owner relationships. Brain potentials were recorded while participants observed increasing and decreasing stock prices. Results showed that observations of stock outcomes among four types of chooser-owner relationships elicited differentiated feedback-related negativity (d-FRN: differences in FRN waves between losses and gains, reflecting violations of expectancy to stock outcomes): (1) Self-chosen-other-owned stocks evoked significantly larger d-FRN discrepancies than self-chosen-self-owned stocks, indicating a greater expectancy violation to others' losses than to one's own, demonstrating a reversed ownership effect. Moreover, people high in conscientiousness showed an increase in this trend, suggesting a stronger other-consideration; (2) Self-chosen-self-owned stocks and other-chosen-self-owned stocks revealed no significant d-FRN discrepancy, showing no choosership effect beyond the ownership effect; (3) Other-chosen-self-owned stocks evoked a significantly stronger d-FRN discrepancy than other-chosen-other-owned stocks, demonstrating an ownership effect; (4) Self-chosen-other-owned stocks evoked a significantly stronger d-FRN discrepancy than other-chosen-other-owned stocks, revealing a choosership effect. These findings suggest that the ownership effect could be reversed by conscientiousness induced by perceived choosership in the agency relationship, while the choosership effect is attenuated and even disappears under the influence of perceived ownership.

23 citations


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5,680 citations

Journal Article
TL;DR: In this article, the authors present a document, redatto, voted and pubblicato by the Ipcc -Comitato intergovernativo sui cambiamenti climatici - illustra la sintesi delle ricerche svolte su questo tema rilevante.
Abstract: Cause, conseguenze e strategie di mitigazione Proponiamo il primo di una serie di articoli in cui affronteremo l’attuale problema dei mutamenti climatici. Presentiamo il documento redatto, votato e pubblicato dall’Ipcc - Comitato intergovernativo sui cambiamenti climatici - che illustra la sintesi delle ricerche svolte su questo tema rilevante.

4,187 citations

01 Jan 1989
TL;DR: In this article, a two-dimensional version of the Pennsylvania State University mesoscale model has been applied to Winter Monsoon Experiment data in order to simulate the diurnally occurring convection observed over the South China Sea.
Abstract: Abstract A two-dimensional version of the Pennsylvania State University mesoscale model has been applied to Winter Monsoon Experiment data in order to simulate the diurnally occurring convection observed over the South China Sea. The domain includes a representation of part of Borneo as well as the sea so that the model can simulate the initiation of convection. Also included in the model are parameterizations of mesoscale ice phase and moisture processes and longwave and shortwave radiation with a diurnal cycle. This allows use of the model to test the relative importance of various heating mechanisms to the stratiform cloud deck, which typically occupies several hundred kilometers of the domain. Frank and Cohen's cumulus parameterization scheme is employed to represent vital unresolved vertical transports in the convective area. The major conclusions are: Ice phase processes are important in determining the level of maximum large-scale heating and vertical motion because there is a strong anvil componen...

3,813 citations

Journal ArticleDOI
TL;DR: The progress in the research and development of CQDs is reviewed with an emphasis on their synthesis, functionalization and technical applications along with some discussion on challenges and perspectives in this exciting and promising field.
Abstract: Fluorescent carbon nanoparticles or carbon quantum dots (CQDs) are a new class of carbon nanomaterials that have emerged recently and have garnered much interest as potential competitors to conventional semiconductor quantum dots. In addition to their comparable optical properties, CQDs have the desired advantages of low toxicity, environmental friendliness low cost and simple synthetic routes. Moreover, surface passivation and functionalization of CQDs allow for the control of their physicochemical properties. Since their discovery, CQDs have found many applications in the fields of chemical sensing, biosensing, bioimaging, nanomedicine, photocatalysis and electrocatalysis. This article reviews the progress in the research and development of CQDs with an emphasis on their synthesis, functionalization and technical applications along with some discussion on challenges and perspectives in this exciting and promising field.

3,514 citations