L
Leng Chee Chang
Researcher at University of Hawaii at Hilo
Publications - 51
Citations - 1444
Leng Chee Chang is an academic researcher from University of Hawaii at Hilo. The author has contributed to research in topics: Sesquiterpene & Cancer. The author has an hindex of 19, co-authored 48 publications receiving 1212 citations. Previous affiliations of Leng Chee Chang include University of Illinois at Chicago.
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Journal ArticleDOI
Potential anti-inflammatory phenolic glycosides from the medicinal plant Moringa oleifera fruits
Sarot Cheenpracha,Eun-Jung Park,Wesley Y. Yoshida,Chaz Barit,Marisa M. Wall,John M. Pezzuto,Leng Chee Chang +6 more
TL;DR: Bioassay-guided isolation and purification of the ethyl acetate extract of Moringa oleifera fruits yielded three new phenolic glycosides that are reported to have potent NO-inhibitory activity and reduced LPS-mediated iNOS expression.
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Butterfly cluster like lamellar BiOBr/TiO2 nanocomposite for enhanced sunlight photocatalytic mineralization of aqueous ciprofloxacin
Jamshaid Rashid,Ammara Abbas,Leng Chee Chang,Aneela Iqbal,Ihsan-ul Haq,Adeela Rehman,Saif Ullah Awan,Muhammad Arshad,Mohsin Rafique,M.A. Barakat +9 more
TL;DR: The present study for the first time reports facile in-situ room temperature synthesis of butterfly cluster like lamellar BiOBr deposited over TiO2 nanoparticles for photocatalytic breakdown of ciprofloxacin (CIP).
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Activity-guided isolation of constituents of Tephrosia purpurea with the potential to induce the phase II enzyme, quinone reductase.
Leng Chee Chang,Clarissa Gerhäuser,Lynda L. Song,Norman R. Farnsworth,John M. Pezzuto,A. D. Kinghorn +5 more
TL;DR: Three inactive compounds of known structure, 3'-methoxydaidzein, desmoxyphyllin B, and 3,9-dihydroxy-8-methoxycoumestan, were isolated and identified and the structure elucidation of compounds 1 and 2 was carried out by spectral data interpretation.
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Bioactive Constituents of Thuja occidentalis
Leng Chee Chang,Lynda L. Song,Eun Jung Park,Lumonadio Luyengi,K. J. Lee,Norman R. Farnsworth,John M. Pezzuto,A. D. Kinghorn +7 more
TL;DR: An ethyl acetate-soluble extract of the combined leaves and twigs of Thuja occidentalis was found to inhibit 12-O-tetradecanoylphorbol 13-acetate (TPA)-induced ornithine decarboxylase (ODC) in cultured mouse epidermal ME 308 cells.
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Flavonoid constituents of Chorizanthe diffusa with potential cancer chemopreventive activity.
Chung Hs,Leng Chee Chang,Sang Kook Lee,Lisa A. Shamon,van Breemen Rb,Rajendra G. Mehta,Norman R. Farnsworth,John M. Pezzuto,A. D. Kinghorn +8 more
TL;DR: An ethyl acetate-soluble extract of Chorizanthe diffusa was found to exhibit significant antioxidant activity, as judged by scavenging stable 1,1-diphenyl-2-picrylhydrazyl (DPPH) free radicals and inhibition of 12-O-tetradecanoylphorbol 13-acetate (TPA)-induced free radical formation with cultured HL-60 cells.