L
Lenka Koklesova
Researcher at Comenius University in Bratislava
Publications - 44
Citations - 1215
Lenka Koklesova is an academic researcher from Comenius University in Bratislava. The author has contributed to research in topics: Medicine & Cancer. The author has an hindex of 12, co-authored 30 publications receiving 432 citations. Previous affiliations of Lenka Koklesova include Jessenius Faculty of Medicine.
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Journal ArticleDOI
Flavonoids in Cancer Metastasis
Alena Liskova,Lenka Koklesova,Marek Samec,Karel Šmejkal,Samson Mathews Samuel,Elizabeth Varghese,Mariam Abotaleb,Kamil Biringer,Erik Kudela,Jan Danko,Mehdi Shakibaei,Taeg Kyu Kwon,Dietrich Büsselberg,Peter Kubatka +13 more
TL;DR: Anti-cancer effects of flavonoids, targeting all phases of carcinogenesis including metastatic progression, should be implemented into clinical cancer research in order to strengthen their potential use in the future targeted prevention and therapy of cancer in high-risk individuals or patients with aggressive cancer disease with metastatic potential.
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Role of microRNA/Epithelial-to-Mesenchymal Transition Axis in the Metastasis of Bladder Cancer
Milad Ashrafizadeh,Kiavash Hushmandi,Mehrdad Hashemi,Mohammad Esmaeil Akbari,Peter Kubatka,Mehdi Raei,Lenka Koklesova,Shahinozzaman,Reza Mohammadinejad,Masoud Najafi,Gautam Sethi,Alan Prem Kumar,Ali Zarrabi +12 more
TL;DR: This review focuses on microRNAs (miRNAs) and their regulatory effect on epithelial-to-mesenchymal transition (EMT) mechanisms that can regulate metastasis ofadder cancer cells.
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Flavonoids against the SARS-CoV-2 induced inflammatory storm.
Alena Liskova,Marek Samec,Lenka Koklesova,Samson Mathews Samuel,Kevin Zhai,Raghad Khalid Al-Ishaq,Mariam Abotaleb,Vladimir Nosal,Karol Kajo,Milad Ashrafizadeh,Ali Zarrabi,Aranka Brockmueller,Mehdi Shakibaei,Peter Sabaka,Ioana Mozos,David Ullrich,Robert Prosecky,Giampiero La Rocca,Martin Caprnda,Dietrich Büsselberg,Luis Rodrigo,Peter Kruzliak,Peter Kubatka +22 more
TL;DR: The potential role of flavonoids in the modulation of signaling pathways that are crucial for COVID-19 disease, particularly those related to inflammation and immunity, was discussed in this paper.
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Flavonoids against the Warburg phenotype-concepts of predictive, preventive and personalised medicine to cut the Gordian knot of cancer cell metabolism.
Marek Samec,Alena Liskova,Lenka Koklesova,Samson Mathews Samuel,Kevin Zhai,Constanze Buhrmann,Elizabeth Varghese,Mariam Abotaleb,Tawar Qaradakhi,Anthony Zulli,Martin Kello,Jan Mojzis,Pavol Zubor,Taeg Kyu Kwon,Mehdi Shakibaei,Dietrich Büsselberg,Gustavo R. Sarria,Olga Golubnitschaja,Peter Kubatka +18 more
TL;DR: Individualised profiling and patient stratification are presented as powerful tools for implementing targeted ‘anti-Warburg’ measures in the context of predictive, preventive and personalised medicine.
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Cell-free nucleic acid patterns in disease prediction and monitoring-hype or hope?
Adriana Torres Crigna,Marek Samec,Lenka Koklesova,Alena Liskova,Frank A. Giordano,Peter Kubatka,Olga Golubnitschaja +6 more
TL;DR: Whether specific patterns of CFNAs in blood, their detection, quantity and quality might be instrumental to predict a disease development/progression and could be further utilised for accompanying diagnostics, targeted prevention, creation of individualised therapy algorithms, therapy monitoring and prognosis is highlighted.