L
Lennard J. M. Dekker
Researcher at Erasmus University Rotterdam
Publications - 76
Citations - 1996
Lennard J. M. Dekker is an academic researcher from Erasmus University Rotterdam. The author has contributed to research in topics: Mass spectrometry & Medicine. The author has an hindex of 24, co-authored 68 publications receiving 1771 citations. Previous affiliations of Lennard J. M. Dekker include Erasmus University Medical Center.
Papers
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Journal ArticleDOI
Sample preparation issues for tissue imaging by imaging MS.
Basak Kükrer Kaletas,Ingrid M. van der Wiel,Jonathan Stauber,Lennard J. M. Dekker,Coşkun Güzel,Johan M. Kros,Theo M. Luider,Ron M. A. Heeren +7 more
TL;DR: The importance of correct sample treatment in case of MALDI and secondary ion MS imaging experiments is reviewed and the experimental requirements for optimal sample preparation are described.
Journal ArticleDOI
Glioblastoma-derived extracellular vesicles modify the phenotype of monocytic cells
Jeroen de Vrij,S L Niek Maas,Kitty M. C. Kwappenberg,Rosalie Schnoor,Anne Kleijn,Lennard J. M. Dekker,Theo M. Luider,Lot de Witte,Manja Litjens,Miriam E. van Strien,Elly M. Hol,Jérôme Kroonen,Pierre A. Robe,Martine L.M. Lamfers,Marco W. Schilham,Marike L. D. Broekman +15 more
TL;DR: GBM‐derived EVs can modify cells of the monocytic lineage, which acquire characteristics that resemble the tumor‐supportive phenotypes observed in patients.
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Exosomal Secretion of Cytoplasmic Prostate Cancer Xenograft-derived Proteins
Flip H. Jansen,Jeroen Krijgsveld,Angelique L. C. T. van Rijswijk,Gert-Jan C.M. van den Bemd,Mirella S. van den Berg,Wytske M. van Weerden,Rob Willemsen,Lennard J. M. Dekker,Theo M. Luider,Guido Jenster +9 more
TL;DR: Although their function is not clearly defined cancer-derived exosomes offer possibilities for the identification of novel biomarkers for PCa, they are suggested to have potential in finding novel markers for prostate cancer.
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Circulating glioma biomarkers
Johan M. Kros,Dana M. Mustafa,Lennard J. M. Dekker,Peter A. E. Sillevis Smitt,Theo M. Luider,Ping-Pin Zheng +5 more
TL;DR: This review highlights various categories of tumor-associated circulating biomarkers identified in blood and cerebrospinal fluid of glioma patients, including circulating tumor cells, exosomes, nucleic acids, proteins, and oncometabolites.
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Multiple sclerosis‐related proteins identified in cerebrospinal fluid by advanced mass spectrometry
Marcel P. Stoop,Lennard J. M. Dekker,Mark K. Titulaer,Peter C. Burgers,Peter A. E. Sillevis Smitt,Theo M. Luider,Rogier Q. Hintzen +6 more
TL;DR: Three differentially expressed proteins in the comparison of MScl vs. CIS and OIND vs. OND were identified: chromogranin A, a potential marker for neurodegeneration; and two important factors in complement‐mediated inflammatory reaction, clusterin and complement C3.