Author
Leon F. Kubena
Other affiliations: Prairie View A&M University, United States Department of Agriculture, Texas A&M University ...read more
Bio: Leon F. Kubena is an academic researcher from Agricultural Research Service. The author has contributed to research in topics: Broiler & Aflatoxin. The author has an hindex of 59, co-authored 202 publications receiving 9752 citations. Previous affiliations of Leon F. Kubena include Prairie View A&M University & United States Department of Agriculture.
Papers published on a yearly basis
Papers
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TL;DR: The HSCAS, when added to the diet of Leghorn and broiler chicks at a level of .5%, significantly diminished the adverse effects of feeding 7.5 mg AFB1/kg of feed, suggesting this agent (and other aluminosilicate congeners) may prove effective in the preventive management of aflatoxicosis.
341 citations
TL;DR: Results indicated that AfB1 and AfG1 were rapidly degraded using 2% O3, while AfB2 andAfG2 were more resistant to oxidation and required higher levels of O3 (20%) for rapid degradation, while FB1 did not correlate with detoxification, since FB1 solutions treated with O3 were still positive in two bioassay systems.
328 citations
TL;DR: It is suggested that incorporation of lactic acid in the drinking water during pretransport FW may reduce Salmonella and Campylobacter contamination of crops and broiler carcasses at processing.
220 citations
TL;DR: It is indicated that HSCAS can diminish many of the adverse effects of dietary AF in the chicken, but it has no effect on T-2 toxicity.
206 citations
TL;DR: It is suggested that HSCAS can modulate the toxicity of AFB1 and AF in the chicken; however, adding activated charcoal to the diet did not appear to have protective properties against the effects of aflatoxin B1 or of a flatoxin.
197 citations
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3,248 citations
TL;DR: It was concluded that the TEF concept is still the most plausible and feasible approach for risk assessment of halogenated aromatic hydrocarbons with dioxinlike properties.
Abstract: An expert meeting was organized by the World Health Organization (WHO) and held in Stockholm on 15-18 June 1997. The objective of this meeting was to derive consensus toxic equivalency factors (TEFs) for polychlorinated dibenzo-p-dioxins (PCDDs) and dibenzofurans (PCDFs) and dioxinlike polychlorinated biphenyls (PCBs) for both human, fish, and wildlife risk assessment. Based on existing literature data, TEFs were (re)evaluated and either revised (mammals) or established (fish and birds). A few mammalian WHO-TEFs were revised, including 1,2,3,7,8-pentachlorinated DD, octachlorinated DD, octachlorinated DF, and PCB 77. These mammalian TEFs are also considered applicable for humans and wild mammalian species. Furthermore, it was concluded that there was insufficient in vivo evidence to continue the use of TEFs for some di-ortho PCBs, as suggested earlier by Ahlborg et al. [Chemosphere 28:1049-1067 (1994)]. In addition, TEFs for fish and birds were determined. The WHO working group attempted to harmonize TEFs across different taxa to the extent possible. However, total synchronization of TEFs was not feasible, as there were orders of a magnitude difference in TEFs between taxa for some compounds. In this respect, the absent or very low response of fish to mono-ortho PCBs is most noticeable compared to mammals and birds. Uncertainties that could compromise the TEF concept were also reviewed, including nonadditive interactions, differences in shape of the dose-response curve, and species responsiveness. In spite of these uncertainties, it was concluded that the TEF concept is still the most plausible and feasible approach for risk assessment of halogenated aromatic hydrocarbons with dioxinlike properties.
3,247 citations
TL;DR: The strategy of using food additives to protect farm animals from the toxin may also provide effective and economical new approaches to protecting human populations.
1,624 citations
TL;DR: Mycotoxins have various acute and chronic effects on humans and animals depending on species and susceptibility of an animal within a species, and ruminants have, however, generally been more resistant to the adverse effects of mycotoxin.
1,542 citations