L
Lewis Y. Geer
Researcher at National Institutes of Health
Publications - 36
Citations - 19200
Lewis Y. Geer is an academic researcher from National Institutes of Health. The author has contributed to research in topics: Conserved Domain Database & Entrez. The author has an hindex of 26, co-authored 34 publications receiving 17581 citations. Previous affiliations of Lewis Y. Geer include Microsoft.
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Journal ArticleDOI
CDD: a Conserved Domain Database for the functional annotation of proteins
Aron Marchler-Bauer,Shennan Lu,John B. Anderson,Farideh Chitsaz,Myra K. Derbyshire,Carol DeWeese-Scott,Jessica H. Fong,Lewis Y. Geer,Renata C. Geer,Noreen R. Gonzales,Marc Gwadz,David I. Hurwitz,John D. Jackson,Zhaoxi Ke,Christopher J. Lanczycki,Fu-Ping Lu,Gabriele H. Marchler,Mikhail Mullokandov,Marina V. Omelchenko,Cynthia L. Robertson,James S. Song,Narmada Thanki,Roxanne A. Yamashita,Dachuan Zhang,Naigong Zhang,Chanjuan Zheng,Stephen H. Bryant +26 more
TL;DR: NCBI’s Conserved Domain Database (CDD) is a resource for the annotation of protein sequences with the location of conserved domain footprints, and functional sites inferred from these footprints.
Journal ArticleDOI
CDD: NCBI's conserved domain database
Aron Marchler-Bauer,Myra K. Derbyshire,Noreen R. Gonzales,Shennan Lu,Farideh Chitsaz,Lewis Y. Geer,Renata C. Geer,Jane He,Marc Gwadz,David I. Hurwitz,Christopher J. Lanczycki,Fu Lu,Gabriele H. Marchler,James S. Song,Narmada Thanki,Zhouxi Wang,Roxanne A. Yamashita,Dachuan Zhang,Chanjuan Zheng,Stephen H. Bryant +19 more
TL;DR: NCBI's CDD, the Conserved Domain Database, enters its 15th year as a public resource for the annotation of proteins with the location of conserved domain footprints and aims at increasing coverage and providing finer-grained classifications of common protein domains.
Journal ArticleDOI
CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.
Aron Marchler-Bauer,Yu Bo,Lianyi Han,Jane He,Christopher J. Lanczycki,Shennan Lu,Farideh Chitsaz,Myra K. Derbyshire,Renata C. Geer,Noreen R. Gonzales,Marc Gwadz,David I. Hurwitz,Fu Lu,Gabriele H. Marchler,James S. Song,Narmada Thanki,Zhouxi Wang,Roxanne A. Yamashita,Dachuan Zhang,Chanjuan Zheng,Lewis Y. Geer,Stephen H. Bryant +21 more
TL;DR: NCBI's Conserved Domain Database (CDD) aims at annotating biomolecular sequences with the location of evolutionarily conserved protein domain footprints, and functional sites inferred from such footprints.
Posted Content
Open Mass Spectrometry Search Algorithm
Lewis Y. Geer,Sanford P. Markey,Jeffrey A. Kowalak,Lukas Wagner,Ming Xu,Dawn M. Maynard,Xiaoyu Yang,Wenyao Shi,Stephen H. Bryant +8 more
TL;DR: The Open Mass Spectrometry Search Algorithm (OMSSA) as mentioned in this paper was designed to be faster than published algorithms in searching large MS/MS datasets for peptide identification.
Journal ArticleDOI
Open mass spectrometry search algorithm.
Lewis Y. Geer,Sanford P. Markey,Jeffrey A. Kowalak,Lukas Wagner,Ming Xu,Dawn M. Maynard,Xiaoyu Yang,Wenyao Shi,Stephen H. Bryant +8 more
TL;DR: The Open Mass Spectrometry Search Algorithm (OMSSA), designed to be faster than published algorithms in searching large MS/MS datasets, matches more spectra from a standard protein cocktail than a comparable algorithm.