L
Li Chen
Researcher at Southern University of Science and Technology
Publications - 26
Citations - 5098
Li Chen is an academic researcher from Southern University of Science and Technology. The author has contributed to research in topics: Computer science & Viral load. The author has an hindex of 8, co-authored 11 publications receiving 3811 citations.
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Journal ArticleDOI
Treatment of 5 Critically Ill Patients With COVID-19 With Convalescent Plasma.
Chenguang Shen,Zhaoqin Wang,Fang Zhao,Yang Yang,Jinxiu Li,Jing Yuan,Fuxiang Wang,Delin Li,Delin Li,Minghui Yang,Li Xing,Jinli Wei,Haixia Xiao,Haixia Xiao,Yan Yang,Jiuxin Qu,Ling Qing,Li Chen,Zhixiang Xu,Ling Peng,Yanjie Li,Haixia Zheng,Feng Chen,Kun Huang,Yujing Jiang,Dongjing Liu,Zheng Zhang,Yingxia Liu,Lei Liu +28 more
TL;DR: In this preliminary uncontrolled case series of 5 critically ill patients with COVID-19 and ARDS, administration of convalescent plasma containing neutralizing antibody was followed by improvement in their clinical status, and these observations require evaluation in clinical trials.
Journal ArticleDOI
Clinical and biochemical indexes from 2019-nCoV infected patients linked to viral loads and lung injury.
Yingxia Liu,Yang Yang,Cong Zhang,Cong Zhang,Fengming Huang,Fuxiang Wang,Jing Yuan,Zhaoqin Wang,Jinxiu Li,Jianming Li,Cheng Feng,Zheng Zhang,Lifei Wang,Ling Peng,Li Chen,Yuhao Qin,Dandan Zhao,Shuguang Tan,Lu Yin,Jun Xu,Cong-Zhao Zhou,Chengyu Jiang,Lei Liu +22 more
TL;DR: The epidemiological, clinical, laboratory, and radiological characteristics, as well as potential biomarkers for predicting disease severity in 2019-nCoV-infected patients in Shenzhen, China, suggest a number of potential diagnosis biomarkers and angiotensin receptor blocker drugs for potential repurposing treatment of 2019- nCoV infection.
Journal ArticleDOI
Experimental Treatment with Favipiravir for COVID-19: An Open-Label Control Study.
Qingxian Cai,Minghui Yang,Dongjing Liu,Jun Chen,Dan Shu,Junxia Xia,Xuejiao Liao,Yuanbo Gu,Qiu’e Cai,Yang Yang,Chenguang Shen,Xiaohe Li,Ling Peng,Deliang Huang,Jing Zhang,Shurong Zhang,Fuxiang Wang,Jiaye Liu,Li Chen,Shuyan Chen,Zhaoqin Wang,Zheng Zhang,Ruiyuan Cao,Wu Zhong,Yingxia Liu,Lei Liu +25 more
TL;DR: In this open-label nonrandomized control study, FPV showed significantly better treatment effects on COVID-19 in terms of disease progression and viral clearance; if causal, these results should be important information for establishing standard treatment guidelines to combat the SARS-CoV-2 infection.
Journal ArticleDOI
Clinical and biochemical indexes from 2019-nCoV infected patients linked to viral loads and lung injury
Yingxia Liu,Yang Yang,Cong Zhang,Cong Zhang,Fengming Huang,Fuxiang Wang,Jing Yuan,Zhaoqin Wang,Jinxiu Li,Jian-ming Li,Cheng Feng,Zheng Zhang,Lifei Wang,Ling Peng,Li Chen,Yuhao Qin,Dandan Zhao,Shuguang Tan,Lu Yin,Jun Xu,Jun Xu,Cong-Zhao Zhou,Chengyu Jiang,Lei Liu +23 more
TL;DR: The results suggest a number of potential diagnosis biomarkers and angiotensin receptor blocker (ARB) drugs for potential repurposing treatment of 2019-nCoV infection.
Journal ArticleDOI
Elevated plasma levels of selective cytokines in COVID-19 patients reflect viral load and lung injury
Yingxia Liu,Cong Zhang,Cong Zhang,Fengming Huang,Yang Yang,Fuxiang Wang,Jing Yuan,Zheng Zhang,Yuhao Qin,Li Xiaoyun,Dandan Zhao,Shunwang Li,Shuguang Tan,Zhaoqin Wang,Jinxiu Li,Chenguang Shen,Jianming Li,Ling Peng,Weibo Wu,Mengli Cao,Li Xing,Zhixiang Xu,Li Chen,Cong-Zhao Zhou,William J. Liu,Lei Liu,Chengyu Jiang +26 more
TL;DR: It is suggested that 2019-nCoV infections trigger extensive changes in a wide array of cytokines, some of which could be potential biomarkers of disease severity of2019-n coV infections.