L
Li Xin
Researcher at Chinese Center for Disease Control and Prevention
Publications - 17
Citations - 731
Li Xin is an academic researcher from Chinese Center for Disease Control and Prevention. The author has contributed to research in topics: Influenza A virus & Virus. The author has an hindex of 9, co-authored 13 publications receiving 636 citations. Previous affiliations of Li Xin include National Health and Family Planning Commission.
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Journal ArticleDOI
Biological features of novel avian influenza A (H7N9) virus
Jiangfang Zhou,Dayan Wang,Rongbao Gao,Baihui Zhao,Jingdong Song,Xian Qi,Yanjun Zhang,Yonglin Shi,Lei Yang,Wenfei Zhu,Tian Bai,Kun Qin,Yu Lan,Shumei Zou,Junfeng Guo,Jie Dong,Libo Dong,Ye Zhang,Hejiang Wei,Xiaodan Li,Jian Lu,Liqi Liu,Xiang Zhao,Xiyan Li,Weijuan Huang,Le-ying Wen,Hong Bo,Li Xin,Y. Chen,Cuilin Xu,Yuquan Pei,Yue Yang,Xiaodong Zhang,Shiwen Wang,Zijian Feng,Jun Han,Weizhong Yang,George F. Gao,Guizhen Wu,Dexin Li,Yu Wang,Yuelong Shu +41 more
TL;DR: It is shown that the emerging H7N9 avian influenza virus poses a potentially high risk to humans, and current seasonal vaccination could not provide protection.
Journal ArticleDOI
Two Outbreak Sources of Influenza A (H7N9) Viruses Have Been Established in China
Dayan Wang,Lei Yang,Wenfei Zhu,Ye Zhang,Shumei Zou,Hong Bo,Rongbao Gao,Jie Dong,Weijuan Huang,Junfeng Guo,Zi Li,Xiang Zhao,Xiaodan Li,Li Xin,Jianfang Zhou,Tao Chen,Libo Dong,Hejiang Wei,Xiyan Li,Liqi Liu,Jing Tang,Yu Lan,Jing Yang,Yuelong Shu +23 more
TL;DR: Both sources in the Yangtze River Delta region and the Pearl RiverDelta region have been established and found to be responsible for the H7N9 outbreaks in mainland China, posing a long-term threat of H7n9 infection in humans.
Journal ArticleDOI
Genetic tuning of the novel avian influenza A(H7N9) virus during interspecies transmission, China, 2013.
Dayan Wang,Limei Yang,Rongbao Gao,Xiaodong Zhang,Y Tan,Aiping Wu,Wenfei Zhu,Jianfang Zhou,Shumei Zou,Xiyan Li,Y Sun,Ye Zhang,Y Liu,T Liu,Ying Xiong,J Xu,L Chen,Y Weng,X Qi,Junfeng Guo,Xiaodan Li,Jinming Dong,Weijuan Huang,Lixin Dong,Xiang Zhao,Liqi Liu,Jian Lu,Yu Lan,Hua Wei,Li Xin,Y. Chen,Cuiling Xu,Tao Chen,Yun Zhu,Tao Jiang,Zijian Feng,Weizhong Yang,Yu Wang,Hongbo Zhu,Yi Guan,George F. Gao,Dexin Li,Jun Han,Shiwen Wang,Guizhen Wu,Yuelong Shu +45 more
TL;DR: A genetic tuning procedure with continuous amino acid substitutions and reassorting that mediates host adaptation and interspecies transmission is proposed and may create opportunities for further adaptation of influenza A(H7N9) and its potential to cause a pandemic.
Journal ArticleDOI
Poultry farms as a source of avian influenza A (H7N9) virus reassortment and human infection
Donglin Wu,Shumei Zou,Tian Bai,Jing Li,Xiang Zhao,Lei Yang,Hongmin Liu,Xiaodan Li,Xianda Yang,Li Xin,Shuang Xu,Xiaohui Zou,Xiyan Li,Ao Wang,Junfeng Guo,Bingxin Sun,Weijuan Huang,Ye Zhang,Xiang Li,Rongbao Gao,Bo Shen,Tao Chen,Jie Dong,Hejiang Wei,Shiwen Wang,Qun Li,Dexin Li,Guizhen Wu,Zijian Feng,George F. Gao,Yu Wang,Dayan Wang,Ming Fan,Yuelong Shu +33 more
TL;DR: It is demonstrated that poultry farms could be a source of reassortment between H7N9 virus and H9N2 virus as well as human infection, which emphasizes the importance to public health of active avian influenza surveillance at poultry farms.
Journal ArticleDOI
A comprehensive surveillance of adamantane resistance among human influenza A virus isolated from mainland China between 1956 and 2009
Yu Lan,Ye Zhang,Libo Dong,Dayan Wang,Weijuan Huang,Li Xin,Limei Yang,Xiang Zhao,Zi Li,Wei Wang,Xiyan Li,Cuilin Xu,Lei Yang,Junfeng Guo,Min Wang,Yousong Peng,Yan Gao,Yuan-ji Guo,Le-ying Wen,Taijiao Jiang,Yuelong Shu +20 more
TL;DR: Because of the high percentage of adamantane-resistant H3N2 and H1N1 viruses in mainland China, the use of amantadine and rimantadines drugs for prophylaxis and treatment of current seasonal influenza A infection is not recommended.