L
Liangkai Cheng
Publications - 1
Citations - 1
Liangkai Cheng is an academic researcher. The author has contributed to research in topics: Mutant & Isothermal titration calorimetry. The author has co-authored 1 publications.
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New insights into the mechanism of Keap1-Nrf2 interaction based on cancer-associated mutations
TL;DR: In this paper, the crystal structure of the Keap1-Kelch domain with Nrf2 25-mer peptide was determined, and the molecular effects of Nrf 2Thr80 and NRF2Pro85 on the binding of Keap 1 by the method isothermal titration calorimetry (ITC), differential scanning fluorimetry, and electrophoretic mobility shift assay (EMSA).