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Lianxin Liu

Researcher at University of Science and Technology of China

Publications -  164
Citations -  6726

Lianxin Liu is an academic researcher from University of Science and Technology of China. The author has contributed to research in topics: Cancer & Internal medicine. The author has an hindex of 41, co-authored 144 publications receiving 4769 citations. Previous affiliations of Lianxin Liu include Peking Union Medical College & Chinese Ministry of Education.

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Guidelines for Diagnosis and Treatment of Primary Liver Cancer in China (2017 Edition).

TL;DR: A guideline on the surveillance, diagnosis, staging, and treatment of HCC occurring in China is presented, and recommendations regarding patients with HCC in China are made to ensure optimum patient outcomes.
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Guidelines for the Diagnosis and Treatment of Hepatocellular Carcinoma (2019 Edition).

Jian Zhou, +77 more
- 11 Nov 2020 - 
TL;DR: The new guidelines were endorsed and promulgated by the Bureau of Medical Administration of the National Health Commission of the People’s Republic of China in December 2019 and reflect the real-world situation in China regarding diagnosing and treating liver cancer in recent years.
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Tumour-associated mutant p53 drives the Warburg effect.

TL;DR: It is shown that tumor-associatedmutp53 stimulates the Warburg effect in cultured cells and mutp53 knock-in mice as a new mutp 53 gain-of-function (GOF) and a mechanism for controlling the Warberg effect is revealed.
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Role of microRNA in anticancer drug resistance

TL;DR: Accumulating evidence is revealing an important role of miRNAs in anticancer drug resistance and miRNA expression profiling can be correlated with the development of antic cancer drug resistance.
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Hypoxia‐mediated sorafenib resistance can be overcome by EF24 through Von Hippel‐Lindau tumor suppressor‐dependent HIF‐1α inhibition in hepatocellular carcinoma

TL;DR: This study tested the hypothesis that hypoxia caused by the antiangiogenic effects of sustained sorafenib therapy could induce sorafinib resistance as a cytoprotective adaptive response, thereby limiting sorAFenib efficiency, and found that sustained SorafenIB therapy led to increased intratumor hypoxIA, which was associated with sorafanib sensitivity in HCC subcutaneous mice tumor models.