Ligen Lin

TL;DR: This paper intends to provide a comprehensive view of a variety of methods used in the extraction and isolation of natural products, presenting the advantage, disadvantage and practical examples of conventional and modern techniques involved in natural products research.

TL;DR: This review comprehensively review therapeutic targets and mechanisms of action, and translational study of triptolide and celastrol, and proposes the use of structural derivatives, targeted therapy, and combination treatment to reduce toxicity and increase therapeutic window of these potent natural products from T. wilfordii Hook F.

TL;DR: It is shown that ablation of the ghrelin receptor (growth hormone secretagogue receptor, GHS‐R) improves insulin sensitivity during aging and improves aging‐associated obesity and insulin resistance by reducing adiposity and increasing thermogenesis.

TL;DR: Various investigations have shown that CR and its main alkaloids exhibited many powerful pharmacological effects including anti-inflammatory, anti-cancer, anti -diabetic, neuroprotective, cardioprotective, hypoglycemic,Anti-Alzheimer and hepatoprotective activities.

TL;DR: This review summarizes the achievements of the investigations in botany, phytochemistry, quality control, traditional uses, pharmacological activities and clinical studies on O. japonicus and describes the shortcomings of studies on this herbal drug, which serves as the basis of further scientific research and development of this traditional herbal drug.