L
Lijun Ding
Researcher at Nanjing University
Publications - 63
Citations - 1915
Lijun Ding is an academic researcher from Nanjing University. The author has contributed to research in topics: Endometrium & Mesenchymal stem cell. The author has an hindex of 18, co-authored 52 publications receiving 1186 citations. Previous affiliations of Lijun Ding include Nanjing Medical University & University of Edinburgh.
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Journal ArticleDOI
Transplantation of bone marrow mesenchymal stem cells on collagen scaffolds for the functional regeneration of injured rat uterus.
Lijun Ding,Xin’an Li,Haixiang Sun,Jing Su,Nacheng Lin,Bruno Péault,Tianran Song,Jun Yang,Jianwu Dai,Yali Hu +9 more
TL;DR: The findings indicate that BM-MSCs may support uterine tissue regeneration and increase proliferative abilities of uterine endometrial and muscular cells, facilitated microvasculature regeneration, and restored the ability of endometrium to receive the embryo and support its development to a viable stage.
Journal ArticleDOI
Allogeneic cell therapy using umbilical cord MSCs on collagen scaffolds for patients with recurrent uterine adhesion: a phase I clinical trial.
Yun Cao,Haixiang Sun,Hui Zhu,Xianghong Zhu,Xiaoqiu Tang,Guijun Yan,Jingmei Wang,Donghui Bai,Juan Wang,Liu Wang,Qi Zhou,Huiyan Wang,Chengyan Dai,Lijun Ding,Biyun Xu,Yan Zhou,Jie Hao,Jianwu Dai,Yali Hu +18 more
TL;DR: Transplanting clinical-grade UC-MSCs loaded onto a degradable collagen scaffold into the uterine cavity of patients with recurrent IUA following adhesiolysis surgery is a safety and effective therapeutic method.
Journal ArticleDOI
MicroRNA-181a Suppresses Mouse Granulosa Cell Proliferation by Targeting Activin Receptor IIA
TL;DR: An interplay between miR-181a and acvr2a is identified, and an important role of miR -181a in regulating granulosa cell proliferation and ovarian follicle development is revealed.
Journal ArticleDOI
miR-181a increases FoxO1 acetylation and promotes granulosa cell apoptosis via SIRT1 downregulation
Mei Zhang,Qun Zhang,Yali Hu,Lu Xu,Yue Jiang,Chunxue Zhang,Lijun Ding,Ruiwei Jiang,Jianxin Sun,Haixiang Sun,Guijun Yan +10 more
TL;DR: It is found that miR-181a was upregulated in hydrogen peroxide-treated GCs and a 3-nitropropionic acid-induced in vivo model of ovarian oxidative stress and Sirtuin 1 (SIRT1), a deacetylase that suppresses FoxO1 acetylation in GCs, was downregulated by miR -181a and reversed the promoting effects of H2O2 and miR
Journal ArticleDOI
MicroRNA-133b stimulates ovarian estradiol synthesis by targeting Foxl2
Anyi Dai,Haixiang Sun,Ting Fang,Qun Zhang,Shaogen Wu,Yue Jiang,Lijun Ding,Guijun Yan,Yali Hu +8 more
TL;DR: It is demonstrated that miR‐133b down‐regulates Foxl2 expression in granulosa cells by directly targeting the 3′UTR, thus inhibiting the Foxl 2‐mediated transcriptional repression of StAR and CYP19A1 to promote estradiol production.