L
Liladhar B. Kumbhare
Researcher at Bhabha Atomic Research Centre
Publications - 25
Citations - 565
Liladhar B. Kumbhare is an academic researcher from Bhabha Atomic Research Centre. The author has contributed to research in topics: Chemistry & Glutathione peroxidase. The author has an hindex of 11, co-authored 23 publications receiving 500 citations.
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Journal ArticleDOI
3,3'-diselenodipropionic acid, an efficient peroxyl radical scavenger and a GPx mimic, protects erythrocytes (RBCs) from AAPH-induced hemolysis.
Amit Kunwar,B. Mishra,Atanu Barik,Liladhar B. Kumbhare,Ruchi Pandey,Vimal K. Jain,K. Indira Priyadarsini +6 more
TL;DR: The results when compared with two well-known selenium compounds, sodium selenite and ebselen, indicated that DSePA, although it shows lesser GPx activity, has higher free radical scavenging ability and lesser toxicity.
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In vivo radioprotection studies of 3,3′-diselenodipropionic acid, a selenocystine derivative
Amit Kunwar,Punit Bansal,S. Jaya Kumar,P. P. Bag,P.J. Paul,Neetinkumar D. Reddy,Liladhar B. Kumbhare,Vikas Jain,R.C. Chaubey,Mazhuvancherry Kesavan Unnikrishnan,K.I. Priyadarsini +10 more
TL;DR: It is confirmed that DSePA exhibits protective effects against whole-body gamma-radiation and the probable mechanisms of action involve the maintenance of antioxidant enzymes, prophylactic action through the attenuation of the DNA damage, and inhibition of apoptosis.
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Pulse radiolysis studies on reactions of hydroxyl radicals with selenocystine derivatives.
TL;DR: From studies of reactions of hydroxyl radicals with selenocystine and two of its analogues, it has been concluded that the electron-donating carboxylic acid group decreases the reduction potential and facilitates quantitative conversion ofHydroxyl radical adducts to radical cations, while the electron -withdrawing NH(3)(+) group not only increases the reductionpotential but also leads to fragmentation of the hydroxy radical adduction to selenyl radicals, which
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Group 12 metal monoselenocarboxylates: synthesis, characterization, structure and their transformation to metal selenide (MSe; M = Zn, Cd, Hg) nanoparticles.
TL;DR: The X-ray structural analysis of [Cd(SeCOPh)2(tmeda)] revealed that the complex is a discrete monomer having an approximate tetrahedral coordination environment around the central metal atom with monodentate (Se-bonded) selenocarboxylates.
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Palladium(II) and platinum(II) 2-(methoxycarbonyl)ethylselenolates:Synthesis, spectroscopy, structures and their conversion into metal selenide
TL;DR: A diselenide has been prepared by esterification of $(HOOCCH2CH_2Se)_2$ in methanol as mentioned in this paper, which enables interconversion of various complexes by manipulating mole ratios of appropriate starting materials.