L
Lillian K. Fritz-Laylin
Researcher at University of Massachusetts Amherst
Publications - 55
Citations - 6997
Lillian K. Fritz-Laylin is an academic researcher from University of Massachusetts Amherst. The author has contributed to research in topics: Naegleria & Pseudopodia. The author has an hindex of 18, co-authored 49 publications receiving 5858 citations. Previous affiliations of Lillian K. Fritz-Laylin include University of California, Berkeley & John Innes Centre.
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Journal ArticleDOI
The Chlamydomonas Genome Reveals the Evolution of Key Animal and Plant Functions
Sabeeha S. Merchant,Simon E. Prochnik,Olivier Vallon,Elizabeth H. Harris,Steven J. Karpowicz,George B. Witman,Astrid Terry,Asaf Salamov,Lillian K. Fritz-Laylin,Laurence Maréchal-Drouard,Wallace F. Marshall,Liang-Hu Qu,David R. Nelson,Anton A. Sanderfoot,Martin H. Spalding,Vladimir V. Kapitonov,Qinghu Ren,Patrick J. Ferris,Erika Lindquist,Harris Shapiro,Susan Lucas,Jane Grimwood,Jeremy Schmutz,Pierre Cardol,Pierre Cardol,Heriberto Cerutti,Guillaume Chanfreau,Chun-Long Chen,Valérie Cognat,Martin T. Croft,Rachel M. Dent,Susan K. Dutcher,Emilio Fernández,Hideya Fukuzawa,David González-Ballester,Diego González-Halphen,Armin Hallmann,Marc Hanikenne,Michael Hippler,William Inwood,Kamel Jabbari,Ming Kalanon,Richard Kuras,Paul A. Lefebvre,Stéphane D. Lemaire,Alexey V. Lobanov,Martin Lohr,Andrea L Manuell,Iris Meier,Laurens Mets,Maria Mittag,Telsa M. Mittelmeier,James V. Moroney,Jeffrey L. Moseley,Carolyn A. Napoli,Aurora M. Nedelcu,Krishna K. Niyogi,Sergey V. Novoselov,Ian T. Paulsen,Greg Pazour,Saul Purton,Jean-Philippe Ral,Diego Mauricio Riaño-Pachón,Wayne R. Riekhof,Linda A. Rymarquis,Michael Schroda,David B. Stern,James G. Umen,Robert D. Willows,Nedra F. Wilson,Sara L. Zimmer,Jens Allmer,Janneke Balk,Katerina Bisova,Chong-Jian Chen,Marek Eliáš,Karla C Gendler,Charles R. Hauser,Mary Rose Lamb,Heidi K. Ledford,Joanne C. Long,Jun Minagawa,M. Dudley Page,Junmin Pan,Wirulda Pootakham,Sanja Roje,Annkatrin Rose,Eric Stahlberg,Aimee M. Terauchi,Pinfen Yang,Steven G. Ball,Chris Bowler,Carol L. Dieckmann,Vadim N. Gladyshev,Pamela J. Green,Richard A. Jorgensen,Stephen P. Mayfield,Bernd Mueller-Roeber,Sathish Rajamani,Richard T. Sayre,Peter Brokstein,Inna Dubchak,David Goodstein,Leila Hornick,Y. Wayne Huang,Jinal Jhaveri,Yigong Luo,Diego Martinez,Wing Chi Abby Ngau,Bobby Otillar,Alexander Poliakov,Aaron Porter,Lukasz Szajkowski,Gregory Werner,Kemin Zhou,Igor V. Grigoriev,Daniel S. Rokhsar,Daniel S. Rokhsar,Arthur R. Grossman +118 more
TL;DR: Analyses of the Chlamydomonas genome advance the understanding of the ancestral eukaryotic cell, reveal previously unknown genes associated with photosynthetic and flagellar functions, and establish links between ciliopathy and the composition and function of flagella.
Journal ArticleDOI
Lattice Light Sheet Microscopy: Imaging Molecules to Embryos at High Spatiotemporal Resolution
Bi-Chang Chen,Wesley R. Legant,Kai Wang,Lin Shao,Daniel E. Milkie,Michael W. Davidson,Chris Janetopoulos,Xufeng S. Wu,John A. Hammer,Zhe Liu,Brian P. English,Yuko Mimori-Kiyosue,Daniel P. Romero,Alex T. Ritter,Alex T. Ritter,Jennifer Lippincott-Schwartz,Lillian K. Fritz-Laylin,R. Dyche Mullins,Diana M. Mitchell,Joshua N. Bembenek,Anne-Cécile Reymann,Ralph Böhme,Stephan W. Grill,Jennifer T. Wang,Geraldine Seydoux,U. Serdar Tulu,Daniel P. Kiehart,Eric Betzig +27 more
TL;DR: A new microscope using ultrathin light sheets derived from two-dimensional optical lattices is developed, demonstrating the performance advantages of lattice light-sheet microscopy compared with previous techniques and highlighted phenomena that, when seen at increased spatiotemporal detail, may hint at previously unknown biological mechanisms.
Journal ArticleDOI
Genomic Analysis of Organismal Complexity in the Multicellular Green Alga Volvox carteri
Simon E. Prochnik,James G. Umen,Aurora M. Nedelcu,Armin Hallmann,Stephen M. Miller,Ichiro Nishii,Patrick J. Ferris,Alan Kuo,Therese Mitros,Lillian K. Fritz-Laylin,Uffe Hellsten,Jarrod Chapman,Oleg Simakov,Stefan A. Rensing,Astrid Terry,Jasmyn Pangilinan,Vladimir V. Kapitonov,Jerzy Jurka,Asaf Salamov,Harris Shapiro,Jeremy Schmutz,Jane Grimwood,Erika Lindquist,Susan Lucas,Igor V. Grigoriev,Rüdiger Schmitt,David L. Kirk,Daniel S. Rokhsar,Daniel S. Rokhsar +28 more
TL;DR: In this paper, the authors sequenced the 138-mega-base pair genome of V. carteri and compared its approximately 14,500 predicted proteins to those of its unicellular relative Chlamydomonas reinhardtii.
Journal ArticleDOI
The Genome of Naegleria gruberi Illuminates Early Eukaryotic Versatility
Lillian K. Fritz-Laylin,Simon E. Prochnik,Michael L. Ginger,Joel B. Dacks,Joel B. Dacks,Meredith L. Carpenter,Mark C. Field,Alan Kuo,Alexander R. Paredez,Jarrod Chapman,Jonathan K Pham,Shengqiang Shu,Rochak Neupane,Michael J. Cipriano,Joel Mancuso,Hank Tu,Asaf Salamov,Erika Lindquist,Harris Shapiro,Susan Lucas,Igor V. Grigoriev,W. Zacheus Cande,Chandler Fulton,Daniel S. Rokhsar,Daniel S. Rokhsar,Scott C. Dawson +25 more
TL;DR: The Naegleria genome facilitates substantially broader phylogenomic comparisons of free-living eukaryotes than previously possible, allowing us to identify thousands of genes likely present in the pan-eukaryotic ancestor, with 40% likely eukARYotic inventions.
Journal ArticleDOI
SuperPlots: Communicating reproducibility and variability in cell biology.
TL;DR: This Viewpoint proposes a simple way to highlight both experimental reproducibility and cell-to-cell variation, while avoiding pitfalls common in analysis of cell biology data.