L
Lin Liu
Researcher at Chinese Academy of Sciences
Publications - 1161
Citations - 32284
Lin Liu is an academic researcher from Chinese Academy of Sciences. The author has contributed to research in topics: Medicine & Biology. The author has an hindex of 78, co-authored 937 publications receiving 24389 citations. Previous affiliations of Lin Liu include Sun Yat-sen University & University of Connecticut.
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Journal ArticleDOI
Alterations of the human gut microbiome in liver cirrhosis
Nan Qin,Fengling Yang,Ang Li,Edi Prifti,Yanfei Chen,Li Shao,Jing Guo,Jian Yao,Lingjiao Wu,Jiawei Zhou,Ni Shujun,Lin Liu,Nicolas Pons,Jean-Michel Batto,Sean Kennedy,Pierre Leonard,Chunhui Yuan,Wenchao Ding,Yuanting Chen,Xinjun Hu,Beiwen Zheng,Guirong Qian,Wei Xu,S. Dusko Ehrlich,Shu-Sen Zheng,Lanjuan Li +25 more
TL;DR: The gut microbiome in liver cirrhosis is characterized by comparing 98 patients and 83 healthy control individuals and on the basis of only 15 biomarkers, a highly accurate patient discrimination index is created and validated on an independent cohort, suggesting microbiota-targeted biomarkers may be a powerful tool for diagnosis of different diseases.
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The mathematics of cancer: integrating quantitative models
TL;DR: The recent expansion of quantitative models addresses many questions regarding tumour initiation, progression and metastases as well as intra-tumour heterogeneity, treatment responses and resistance.
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A randomized, controlled trial of acceptance and commitment therapy and cognitive-behavioral therapy for chronic pain
Julie Loebach Wetherell,Julie Loebach Wetherell,Niloofar Afari,Niloofar Afari,Thomas Rutledge,Thomas Rutledge,John T. Sorrell,Jill A. Stoddard,Andrew J. Petkus,Brittany C. Solomon,David Lehman,David Lehman,Lin Liu,Ariel J. Lang,J. Hampton Atkinson,J. Hampton Atkinson +15 more
TL;DR: It is suggested that ACT is an effective and acceptable adjunct intervention for patients with chronic pain and cognitive‐behavioral therapy may be more satisfactory.
Journal ArticleDOI
Telomere lengthening early in development.
Lin Liu,Susan M. Bailey,Maja Okuka,Purificación Muñoz,Chao Li,Lingjun Zhou,Chao Wu,Eva Czerwiec,Laurel L. Sandler,Andreas Seyfang,Maria A. Blasco,David L. Keefe +11 more
TL;DR: It is suggested that telomeres lengthen during the early cleavage cycles following fertilization through a recombination-based mechanism, and that from the blastocyst stage onwards, telomerase only maintains the telomere length established by this alternative mechanism.
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Telomere elongation in induced pluripotent stem cells from dyskeratosis congenita patients
Suneet Agarwal,Suneet Agarwal,Yuin-Han Loh,Yuin-Han Loh,Erin M. McLoughlin,Erin M. McLoughlin,Junjiu Huang,Junjiu Huang,In-Hyun Park,In-Hyun Park,Justine D. Miller,Justine D. Miller,Hongguang Huo,Hongguang Huo,Maja Okuka,Rosana Maria dos Reis,Sabine Loewer,Sabine Loewer,Huck-Hui Ng,David L. Keefe,Frederick D. Goldman,Aloysius J. Klingelhutz,Lin Liu,Lin Liu,George Q. Daley,George Q. Daley,George Q. Daley +26 more
TL;DR: It is demonstrated that reprogramming restores telomere elongation in DC cells despite genetic lesions affecting telomerase, and it is shown that strategies to increase TERC expression may be therapeutically beneficial in DC patients.