L
Lin Liu
Researcher at University of Science and Technology of China
Publications - 4
Citations - 492
Lin Liu is an academic researcher from University of Science and Technology of China. The author has contributed to research in topics: microRNA & Granulosa cell. The author has an hindex of 4, co-authored 4 publications receiving 449 citations.
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Journal ArticleDOI
MicroRNA-224 Is Involved in Transforming Growth Factor-β-Mediated Mouse Granulosa Cell Proliferation and Granulosa Cell Function by Targeting Smad4
TL;DR: This is the first demonstration that miRNAs can control reproductive functions resulting in promoting TGF-beta1-induced GC proliferation and ovarian estrogen release.
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Transactivation of microRNA-383 by steroidogenic factor-1 promotes estradiol release from mouse ovarian granulosa cells by targeting RBMS1
TL;DR: The results suggest that miR-383 functions to promote steroidogenesis by targeting RBMS1, at least in part, through inactivation of c-Myc, and SF-1 acts as a positive regulator of miR's processing and function in GC.
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Transcriptional cooperation between p53 and NF-κB p65 regulates microRNA-224 transcription in mouse ovarian granulosa cells
Meng Liang,Guidong Yao,Guidong Yao,Mianmian Yin,Mingrong Lü,Hui Tian,Lin Liu,Jie Lian,Xingxu Huang,Fei Sun +9 more
TL;DR: Results showed that both the tumor suppressor gene p53 and NF-κB p65 subunit suppressed the TGF-β1-induced increase in pri-miR-224 expression in GCs, and provided new data about the interplay between transcription factors involved in GC proliferation and function by cooperatively regulating miRNA expression.
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MicroRNA-302a sensitizes testicular embryonal carcinoma cells to cisplatin-induced cell death.
TL;DR: Targeting miR‐302a may offer new therapeutic interventions in TGCT by significantly increased the sensitivity of NT2 cells to cisplatin by enhancing cisPlatin‐induced G2/M phase arrest and the subsequent progression to apoptosis.