Lingam Vijaya

TL;DR: A collaborative genome-wide association study, including >17,100 advanced AMD cases and >60,000 controls of European and Asian ancestry, identifies 19 loci associated at P < 5 × 10−8, which show enrichment for genes involved in the regulation of complement activity, lipid metabolism, extracellular matrix remodeling and angiogenesis.

TL;DR: South Indian eyes with angle closure glaucoma and occludable angles seem to have significantly shorter axial lengths, shallower anterior chambers and greater lens thickness compared to the normal group.

TL;DR: The prevalence of POAG in a > or =40-year-old south Indian urban population was 3.51%, higher than that of the rural population, and in both populations, increasing IOP and older age were associated with the disease.

TL;DR: A genome-wide association study including 1,854 PACG cases and 9,608 controls across 5 sample collections in Asia suggests possible mechanisms explaining the pathogenesis of PACG.

TL;DR: The reported age and gender stratified prevalence estimates from these studies and the Indian population census estimates are used to calculate the number of persons with glaucoma or at risk of the disease in the country.