Lisa Glazenburg

TL;DR: It is demonstrated that microinjection of DNA constructs into fertilized one-cell stage eggs, followed by a low dose of irradiation, frequently results in random integration of the transgene in the genome and its stable transmission through the germline.

TL;DR: This review focuses on morbillivirus‐induced neuropathologies with emphasis on aetiopathogenesis of CNS demyelination and the possible involvement of a morbillvirus in the pathogenesis of multiple sclerosis.

TL;DR: The results suggest that 5-HT(4) agonists may have therapeutic potential in multiple sclerosis by inhibiting the up-regulation of immune responsiveness of astrocytes in the central nervous system.

TL;DR: It is proposed that M. lignano represents a novel powerful model for molecular studies of aging attenuation, and the identified aging gene expression patterns provide a valuable resource for further exploration of anti‐aging strategies.

TL;DR: Using immunocytochemistry in cultured astrocytes derived from newborn Wistar rats, it was found that simvastatin at nanomolar concentrations inhibited, in a dose-response fashion, up to 70% of IFN-γ-induced MHC class II expression, which was reversed by the HMG-CoA reductase product mevalonate.