Lisa J. Wilmes

TL;DR: The correlative relationship between microvasculature changes and tumor growth inhibition supports DCE-MRI methods as a biomarker of VEGF receptor target inhibition with potential clinical utility and suggests 3D MRI-based volume measurements are more sensitive than caliper measurements for detecting small changes in tumor volume.

TL;DR: MRI may provide a volumetric measure more representative of breast composition than mammography, particularly in groups of women with dense breasts, and could potentially be quantified and used for a better assessment of breast cancer risk in these populations.

TL;DR: The breast tissue index could become a common measure for future studies of using noncontrast MRI data because it correlated well with mammographic densities.

TL;DR: Robust fat suppression is important for accurate breast ADC measures and optimal lesion conspicuity on DWI and there were systematic underestimations of ADC for both tumor and normal breast tissue due to intravoxel contribution from fat signal on non-fat-suppressed DWI.

TL;DR: Differences in ADC distribution parameters and qualitative image features suggest that the sequences differ in their ability to capture tumor heterogeneity, suggesting that rFOV DW MRI may be valuable in imaging the lower ADCs expected to correspond to viable tumor in most invasive breast cancers.