Lisa N Miller

TL;DR: In this paper, a meta-analysis correlated polysomnographic sleep findings with psychophysiological reactivity to the danger (CS+) and safety stimuli (CS-), to clarify the specific role of sleep stages before and after extinction learning and extinction recall.

TL;DR: In this paper, a systematic review examined 69 studies across affective and non-affective auditory and visual paradigms and found that trauma exposure is associated with enhanced early processing of incoming stimuli, and PTSD with enhanced processing of affective stimuli and impaired processing of nonaffective stimuli.

TL;DR: In this article, the skin conductance response (SCR) amplitude indexing level of conditioned fear was measured to examine fear reinstatement, and no significant effects of estradiol were found for acquisition of fear conditioning or fear extinction learning.

TL;DR: In this paper , the authors review how human paradigms can successfully translate animal findings to human subjects, with the view that substantially increased insight into the effect of endocannabinoid signalling on stress responding, emotional and intrusive memories, and fear extinction can be gained using modern paradigmms and methods for assessing the state of the endocannaloid system in PTSD.

TL;DR: In this paper, the authors review how human paradigms can successfully translate animal findings to human subjects, with the view that substantially increased insight into the effect of endocannabinoid signalling on stress responding, emotional and intrusive memories, and fear extinction can be gained using modern paradigmms and methods for assessing the state of the endocannaloid system in PTSD.

TL;DR: This article conducted a meta-analysis of the available studies to demonstrate that, for most outcome measures, fear learning using a traumatic film clip unconditional stimulus yields results similar to those seen with an electro-tactile unconditional stimulus, which implies that the combined paradigm shares at least some properties of more standard fear conditioning paradigms.

TL;DR: In this paper , the authors compared the efficacy and acceptability of all published psychotherapeutic and pharmacological interventions for trauma-related nightmares (TRN) in adults and found that Prazosin and image rehearsal therapy (IRT) were the two effective interventions for TRN.

TL;DR: Safety learning creates associations between conditional stimuli and the absence of threat as mentioned in this paper , and the neurobiology of safety learning can be conceptualized along an acquisition-expression model, with the aim of stimulating richer brain-based characterisations of this important process.