L
Lisheng Peng
Researcher at Sun Yat-sen University
Publications - 33
Citations - 614
Lisheng Peng is an academic researcher from Sun Yat-sen University. The author has contributed to research in topics: Neuromyelitis optica & Myelin oligodendrocyte glycoprotein. The author has an hindex of 11, co-authored 33 publications receiving 331 citations.
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Journal ArticleDOI
The glucagon-like peptide-1 receptor agonist reduces inflammation and blood-brain barrier breakdown in an astrocyte-dependent manner in experimental stroke
Yilong Shan,Sha Tan,Yinyao Lin,Siyuan Liao,Bingjun Zhang,Xiaodong Chen,Jihui Wang,Zhezhi Deng,Qin Zeng,Lei Zhang,Yuge Wang,Xueqiang Hu,Wei Qiu,Lisheng Peng,Zhengqi Lu +14 more
TL;DR: Ex-4 improved neurologic deficit scores, reduced the infarct area, and ameliorated BBB breakdown as well as decreased astrocyte-derived VEGF-A, MMP-9, CXCL-1, and MCP-1 levels in ischemic brain tissues from rats subjected to middle cerebral artery occlusion.
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Targeted homing of CCR2-overexpressing mesenchymal stromal cells to ischemic brain enhances post-stroke recovery partially through PRDX4-mediated blood-brain barrier preservation.
Yinong Huang,Jiancheng Wang,Jianye Cai,Yuan Qiu,Haiqing Zheng,Xiaofan Lai,Xin Sui,Yi Wang,Qiying Lu,Yanan Zhang,Meng Yuan,Jin Gong,Wei Cai,Xin Liu,Yilong Shan,Zhezhi Deng,Yue Shi,Yaqing Shu,Lei Zhang,Wei Qiu,Lisheng Peng,Jie Ren,Zhengqi Lu,Andy Peng Xiang +23 more
TL;DR: It is suggested that overexpression of CCR2 on MSCs enhances their targeted migration to the ischemic hemisphere and improves the therapeutic outcomes, which is attributed to the PRDX4-mediated BBB preservation.
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Dysregulated MicroRNA Involvement in Multiple Sclerosis by Induction of T Helper 17 Cell Differentiation.
TL;DR: The possible mechanisms of miRNAs in MS pathophysiology by regulating CD4+ T cell differentiation into Th17 cells, and potential miRNA targets for current disease-modifying treatments are discussed.
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Different features between pediatric-onset and adult-onset patients who are seropositive for MOG-IgG: A multicenter study in South China
Lu Chen,Chen Chen,Xiaonan Zhong,Xiaobo Sun,Haixia Zhu,Xiaojing Li,Hui Yang,Yaqing Shu,Yanyu Chang,Xueqiang Hu,Zhengqi Lu,Lisheng Peng,Wei Qiu +12 more
TL;DR: Distinctive features are present between pediatric-ONSet and adult-onset patients with MOG-IgG, and the different underlying pathogenesis of MOG antibody at different ages is determined.
Journal ArticleDOI
Infections in neuromyelitis optica spectrum disorder.
Xiaonan Zhong,Yifan Zhou,Tingting Lu,Zhanhang Wang,Ling Fang,Lisheng Peng,Allan G. Kermode,Allan G. Kermode,Allan G. Kermode,Wei Qiu +9 more
TL;DR: In this article, the authors summarized studies that either support or present evidence against the hypothesized association between infection and NMOSD and provided some beneficial properties that infectious elements may have based on the hygiene hypothesis.