L
Lívia do Carmo Silva
Researcher at Universidade Federal de Goiás
Publications - 28
Citations - 163
Lívia do Carmo Silva is an academic researcher from Universidade Federal de Goiás. The author has contributed to research in topics: Medicine & Biology. The author has an hindex of 5, co-authored 16 publications receiving 90 citations. Previous affiliations of Lívia do Carmo Silva include Laboratory of Molecular Biology.
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Journal ArticleDOI
Transcriptome Profile of the Response of Paracoccidioides spp. to a Camphene Thiosemicarbazide Derivative
Lívia do Carmo Silva,Diana Patrícia Tamayo Ossa,Symone Vitoriano da Conceição Castro,Ludmila Bringel Pires,Cecília M. A. de Oliveira,Cleuza C. da Silva,Narcimário P. Coelho,Alexandre Melo Bailão,Juliana Alves Parente-Rocha,Célia Maria de Almeida Soares,Orville Hernandez Ruiz,Juan Guillermo McEwen Ochoa,Maristela Pereira +12 more
TL;DR: Evaluated the antifungal activity of a camphene thiosemicarbazide derivative (TSC-C) compound on Paracoccidioides yeast and suggested that TSC-C is a promising candidate for PCM treatment.
Journal ArticleDOI
Proteomic profile response of Paracoccidioides lutzii to the antifungal argentilactone.
Renata Silva do Prado,Alexandre Melo Bailão,Lívia do Carmo Silva,Cecília M. A. de Oliveira,Monique Ferreira Marques,Luciano P. Silva,Elisângela de Paula Silveira-Lacerda,Aliny Pereira de Lima,Célia Maria de Almeida Soares,Maristela Pereira +9 more
TL;DR: Alternative metabolic pathways adopted by the fungi were elucidated, helping to elucidate the course of action of the compound studied and indicated that the fungus has a global metabolic adaptation in the presence of argentilactone.
Journal ArticleDOI
Effects of Argentilactone on the Transcriptional Profile, Cell Wall and Oxidative Stress of Paracoccidioides spp.
Felipe Souto Araújo,Luciene Melo Coelho,Lívia do Carmo Silva,Benedito Rodrigues da Silva Neto,Juliana Alves Parente-Rocha,Alexandre Melo Bailão,Cecília M. A. de Oliveira,Gabriel Fernandes,Orville Hernández,Juan Guillermo McEwen Ochoa,Célia Maria de Almeida Soares,Maristela Pereira +11 more
TL;DR: Evaluated the transcriptional profile of Paracoccidioides lutzii exposed to argentilactone, a constituent of the essential oil of Hyptis ovalifolia, and results suggest that argentILactone is a potential candidate for antifungal therapy.
Journal ArticleDOI
Computer-aided identification of novel anti-paracoccidioidomycosis compounds.
Lívia do Carmo Silva,Bruno J. Neves,Marcelo N. Gomes,Marcelo N. Gomes,Cleber C. Melo-Filho,Célia Ma Soares,Carolina Horta Andrade,Maristela Pereira +7 more
TL;DR: The shape-based virtual screening allowed us to discover promising compounds in prospective hit-to-lead optimization studies for tackling PCM, and showed that most promising hit displayed additive effects with the antifungal cotrimoxazole and amphotericin B.
Journal ArticleDOI
Overview of Antifungal Drugs against Paracoccidioidomycosis: How Do We Start, Where Are We, and Where Are We Going?
Lívia do Carmo Silva,Lívia do Carmo Silva,Amanda Alves de Oliveira,Amanda Alves de Oliveira,Dienny Rodrigues de Souza,Dienny Rodrigues de Souza,Katheryne Lohany Barros Barbosa,Katheryne Lohany Barros Barbosa,Kleber Santiago Freitas E Silva,Marcos Antonio Batista de Carvalho Júnior,Olívia Basso Rocha,Raisa Melo Lima,Raisa Melo Lima,Thaynara Gonzaga Santos,Thaynara Gonzaga Santos,Célia Maria de Almeida Soares,Maristela Pereira +16 more
TL;DR: This review aims to discuss the aspects related to the identification of compounds, methodologies, and perspectives when proposing new antifungal agents against PCM.