Loïc Meunier

TL;DR: It is demonstrated that in-line NIR measurements associated with multivariate analyses can be implemented to monitor in real-time a pan coating operation in order to fulfil the expectations of ICH Q8 guideline on pharmaceutical development, especially in terms of PAT control strategy and reduced end-product testing.

TL;DR: A near infrared (NIR) method was developed for determination of tablet potency of active pharmaceutical ingredient (API) in a complex coated tablet matrix and an easy to use graphical interface was developed to easily determine if the predictions are within the specifications defined by the regulatory organisation.

TL;DR: In this article, the industrial synthesis process for a benzamide derivative and its use as a medicine has been described, which yields a compound of formula (1) with satisfactory purity from the pharmaceutical point of view and in an effective yield from the industrial view of view, as well as crystalline form I thereof.

TL;DR: In this paper, the authors present an X-ray diffraction pattern on powder having diffraction lines as given in the specification, which is used for synthesizing 4-{3]-hexahydrocyclopenta[c]pyrrol-2(1H)-yl]propoxy}benzamide hydrochloride.

TL;DR: The GEN-ERA toolbox can be used to infer completely reproducible comparative genomic and metabolic analyses on prokaryotes and small eukaryotes, and can be useful for other applications, as shown by a case study on Gloeobacterales.