L
Lora Giangregorio
Researcher at University of Waterloo
Publications - 200
Citations - 9626
Lora Giangregorio is an academic researcher from University of Waterloo. The author has contributed to research in topics: Osteoporosis & Medicine. The author has an hindex of 37, co-authored 176 publications receiving 7420 citations. Previous affiliations of Lora Giangregorio include University Health Network & National Institutes of Health.
Papers
More filters
Journal ArticleDOI
A tutorial on pilot studies: the what, why and how
Lehana Thabane,Lehana Thabane,Jinhui Ma,Jinhui Ma,Rong Chu,Rong Chu,Ji Cheng,Ji Cheng,Afisi S. Ismaila,Afisi S. Ismaila,Lorena P. Rios,Lorena P. Rios,Reid Robson,Marroon Thabane,Lora Giangregorio,Charles H. Goldsmith,Charles H. Goldsmith +16 more
TL;DR: A detailed examination of the key aspects of pilot studies for phase III trials including the general reasons for conducting a pilot study, the relationships between pilot studies, proof-of-concept studies, and adaptive designs, and some suggestions on how to report the results of pilot investigations using the CONSORT format.
Journal ArticleDOI
A tutorial on sensitivity analyses in clinical trials: the what, why, when and how
Lehana Thabane,Lawrence Mbuagbaw,Lawrence Mbuagbaw,Shiyuan Zhang,Shiyuan Zhang,Zainab Samaan,Maura Marcucci,Maura Marcucci,Chenglin Ye,Chenglin Ye,Marroon Thabane,Lora Giangregorio,Brittany B. Dennis,Brittany B. Dennis,Daisy Kosa,Daisy Kosa,Daisy Kosa,Victoria Borg Debono,Victoria Borg Debono,Rejane Dillenburg,Vincent Fruci,Monica Bawor,Juneyoung Lee,George A. Wells,Charles H. Goldsmith,Charles H. Goldsmith,Charles H. Goldsmith +26 more
TL;DR: When reporting on a clinical trial, it is recommended to include planned or posthoc sensitivity analyses, the corresponding rationale and results along with the discussion of the consequences of these analyses on the overall findings of the study.
Journal ArticleDOI
FRAX underestimates fracture risk in patients with diabetes
Lora Giangregorio,William D. Leslie,Lisa M. Lix,Helena Johansson,Anders Odén,Eugene V. McCloskey,John A. Kanis +6 more
TL;DR: FRAX underestimated observed major osteoporotic and hip fracture risk in diabetics but demonstrated good concordance with observed fractures for nondiabetics, suggesting that diabetes might be considered for inclusion in future iterations of FRAX.
Journal ArticleDOI
Bone loss and muscle atrophy in spinal cord injury: epidemiology, fracture prediction, and rehabilitation strategies.
Lora Giangregorio,Neil McCartney +1 more
TL;DR: A number of interventions, including standing, electrically stimulated cycling or resistance training, and walking exercises have been explored with the aim of reducing bone loss and/or increasing bone mass and muscle mass in individuals with spinal cord injury as mentioned in this paper.
Journal ArticleDOI
Fragility Fractures and the Osteoporosis Care Gap: An International Phenomenon
TL;DR: The majority of individuals who sustain fragility fractures are not receiving adequate osteoporosis management, and future research should address barriers to appropriate management and the efficacy of implementation strategies designed to close the osteopsorosis care gap.