Louis A. Brunsting

TL;DR: For patients with cardiomyopathy and severe mitral regurgitation, mitral valve reconstruction as opposed to replacement can be accomplished with low operative and early mortality, yielding improvement in symptomatic status and survival.

TL;DR: In this article, retrograde cerebral perfusion with continuous monitoring of cerebral hemoglobin oxygen saturation during hypothermic circulatory arrest in 35 patients who underwent thoracic aortic operations or resection of intracardiac tumor.

TL;DR: The role of the myocardial adenosine 5'-triphosphate (ATP) catabolites, hypoxanthine and xanthine, generated during ischemia and the early phase of reperfusion, in reperfusions injury was assessed by modulatingAdenosine transport and metabolism with specific metabolic inhibitors.

TL;DR: It is suggested that polarized arrest can decrease myocardial metabolic demands below that of depolarized arrest, a plausible mechanism is a reduction in myocardian wall tension caused by decreased calcium influx mediated by the Na-Ca exchanger.

TL;DR: The pharmacokinetic data provide information necessary to the design and application of spin traps to detect oxy radicals during reperfusion of ischemic tissue and suggest the feasibility of monitoring free-radical processes in intact, functioning mammalian tissues by using a low-frequency electron spin resonance spectrometer.