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Louis K. Chang

Researcher at University of California, Los Angeles

Publications -  25
Citations -  1095

Louis K. Chang is an academic researcher from University of California, Los Angeles. The author has contributed to research in topics: Visual acuity & Ranibizumab. The author has an hindex of 13, co-authored 23 publications receiving 982 citations. Previous affiliations of Louis K. Chang include Manhattan Eye, Ear and Throat Hospital & Celgene.

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Journal ArticleDOI

Tears of the retinal pigment epithelium: an old problem in a new era.

TL;DR: RPE tears may develop during the course of anti-VEGF therapy for age-related macular degeneration–related PED in patients with high-risk lesions, especially large irregular PED associated with CNV, which may limit visual prognosis.
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Disruption of the photoreceptor inner segment-outer segment junction in eyes with macular holes.

TL;DR: The photoreceptor layer appears to be involved for a much larger area than that occupied by the macular hole itself, and the abnormality in the IS–OS boundary line may reflect perturbation of a higher level of retinal organization and not an absolute loss of photoreceptors.
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PREDICTORS OF Anti-VEGF-ASSOCIATED RETINAL PIGMENT EPITHELIAL TEAR USING FA AND OCT ANALYSIS

TL;DR: Large PED basal diameter and vertical height are correlated with an increased risk of developing an RPE tear after anti-VEGF therapy, and patients with large vascularized PED by fluorescein angiography and/or OCT analysis should be alerted of the risk for vision loss due to R PE tear afterAnti-VE GF therapy.
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Ultrastructural correlation of spectral-domain optical coherence tomographic findings in vitreomacular traction syndrome.

TL;DR: The adhesion between the vitreous and fovea in vitreomacular traction syndrome is accompanied by fibrocellular proliferation along the exposed surfaces of the inner retina and the posterior surface of the Vitreous, which may account for the prominent OCT signal seen along the posteriorsurface of the vitREous in these cases.