Luca Cardelli

Bio: Luca Cardelli is an academic researcher from University of Oxford. The author has contributed to research in topics: Process calculus & Ambient calculus. The author has an hindex of 73, co-authored 269 publications receiving 21679 citations. Previous affiliations of Luca Cardelli include University of Edinburgh & Bell Labs.

On understanding types, data abstraction, and polymorphism

Abstract: Our objective is to understand the notion of type in programming languages, present a model of typed, polymorphic programming languages that reflects recent research in type theory, and examine the relevance of recent research to the design of practical programming languages.Object-oriented languages provide both a framework and a motivation for exploring the interaction among the concepts of type, data abstraction, and polymorphism, since they extend the notion of type to data abstraction and since type inheritance is an important form of polymorphism. We develop a l-calculus-based model for type systems that allows us to explore these interactions in a simple setting, unencumbered by complexities of production programming languages.The evolution of languages from untyped universes to monomorphic and then polymorphic type systems is reviewed. Mechanisms for polymorphism such as overloading, coercion, subtyping, and parameterization are examined. A unifying framework for polymorphic type systems is developed in terms of the typed l-calculus augmented to include binding of types by quantification as well as binding of values by abstraction.The typed l-calculus is augmented by universal quantification to model generic functions with type parameters, existential quantification and packaging (information hiding) to model abstract data types, and bounded quantification to model subtypes and type inheritance. In this way we obtain a simple and precise characterization of a powerful type system that includes abstract data types, parametric polymorphism, and multiple inheritance in a single consistent framework. The mechanisms for type checking for the augmented l-calculus are discussed.The augmented typed l-calculus is used as a programming language for a variety of illustrative examples. We christen this language Fun because fun instead of l is the functional abstraction keyword and because it is pleasant to deal with.Fun is mathematically simple and can serve as a basis for the design and implementation of real programming languages with type facilities that are more powerful and expressive than those of existing programming languages. In particular, it provides a basis for the design of strongly typed object-oriented languages.

A Theory of Objects

Abstract: From the Publisher: Procedural languages are generally well understood. Their foundations have been cast in calculi that prove useful in matters of implementation and semantics. So far, an analogous understanding has not emerged for object-oriented languages. In this book the authors take a novel approach to the understanding of object-oriented languages by introducing object calculi and developing a theory of objects around them. The book covers both the semantics of objects and their typing rules, and explains a range of object-oriented concepts, such as self, dynamic dispatch, classes, inheritance, prototyping, subtyping, covariance and contravariance, and method specialization. Researchers and graduate students will find this an important development of the underpinnings of object-oriented programming.

Mobile ambients

Abstract: We introduce a calculus describing the movement of processes and devices, including movement through administrative domains.

A semantics of multiple inheritance

Abstract: There are two major ways of structuring data in programming languages. The first and common one, used for example in Pascal, can be said to derive from standard branches of mathematics. Data are organized as Cartesian products (i.e., record types), disjoint sums (i.e., unions or variant types), and function spaces (i.e., functions and procedures). The second method can be said to derive from biology and taxonomy. Data are organized in a hierarchy of classes and subclasses, and data at any level of the hierarchy inherit all the attributes of data higher up in the hierarchy. The top level of this hierarchy is usually called the class of all objects; every datum is an object and every datum inherits the basic properties of objects, e.g., the ability to tell whether two objects are the same or not. Functions and procedures are considered as local actions of objects, as opposed to global operations acting over objects. These different ways of structuring data have generated distinct classes of programming languages, and induced different programming styles. Programming with taxonomically organized data is often called objectoriented programming, and has been advocated as an effective way of structuring programming environments, data bases, and large systems in general. The notions of inheritance and object-oriented programming first appeared in Simula 67 (Dahl, 1966). In Simula, objects are grouped into classes and classes can be organized into a subclass hierarchy. Objects are similar to records with functions as components, and elements of a class can appear wherever elements of the respective superclasses are expected. Subclasses inherit all the attributes of their superclasses. In Simula, the issues are somewhat complicated by the use of objects as coroutines, so that communication between objects can be implemented as message passing between processes. Smalltalk (Goldberg, 1983) adopts and exploits the idea of inheritance, with some changes. While stressing the message-passing paradigm, a

Explicit substitutions

Abstract: The ls-calculus is a refinement of the l-calculus where substitutions are manipulated explicitly. The ls-calculus provides a setting for studying the theory of substitutions, with pleasant mathematical properties. It is also a useful bridge between the classical l-calculus and concrete implementations.

I and i

Abstract: There is, I think, something ethereal about i —the square root of minus one. I remember first hearing about it at school. It seemed an odd beast at that time—an intruder hovering on the edge of reality. Usually familiarity dulls this sense of the bizarre, but in the case of i it was the reverse: over the years the sense of its surreal nature intensified. It seemed that it was impossible to write mathematics that described the real world in …

疟原虫var基因转换速率变化导致抗原变异[英]／Paul H, Robert P, Christodoulou Z, et al//Proc Natl Acad Sci U S A

Abstract: 抗原变异可使得多种致病微生物易于逃避宿主免疫应答。表达在感染红细胞表面的恶性疟原虫红细胞表面蛋白1（PfPMP1）与感染红细胞、内皮细胞、树突状细胞以及胎盘的单个或多个受体作用，在黏附及免疫逃避中起关键的作用。每个单倍体基因组var基因家族编码约60种成员，通过启动转录不同的var基因变异体为抗原变异提供了分子基础。

Machine learning

Abstract: Machine Learning is the study of methods for programming computers to learn. Computers are applied to a wide range of tasks, and for most of these it is relatively easy for programmers to design and implement the necessary software. However, there are many tasks for which this is difficult or impossible. These can be divided into four general categories. First, there are problems for which there exist no human experts. For example, in modern automated manufacturing facilities, there is a need to predict machine failures before they occur by analyzing sensor readings. Because the machines are new, there are no human experts who can be interviewed by a programmer to provide the knowledge necessary to build a computer system. A machine learning system can study recorded data and subsequent machine failures and learn prediction rules. Second, there are problems where human experts exist, but where they are unable to explain their expertise. This is the case in many perceptual tasks, such as speech recognition, hand-writing recognition, and natural language understanding. Virtually all humans exhibit expert-level abilities on these tasks, but none of them can describe the detailed steps that they follow as they perform them. Fortunately, humans can provide machines with examples of the inputs and correct outputs for these tasks, so machine learning algorithms can learn to map the inputs to the outputs. Third, there are problems where phenomena are changing rapidly. In finance, for example, people would like to predict the future behavior of the stock market, of consumer purchases, or of exchange rates. These behaviors change frequently, so that even if a programmer could construct a good predictive computer program, it would need to be rewritten frequently. A learning program can relieve the programmer of this burden by constantly modifying and tuning a set of learned prediction rules. Fourth, there are applications that need to be customized for each computer user separately. Consider, for example, a program to filter unwanted electronic mail messages. Different users will need different filters. It is unreasonable to expect each user to program his or her own rules, and it is infeasible to provide every user with a software engineer to keep the rules up-to-date. A machine learning system can learn which mail messages the user rejects and maintain the filtering rules automatically. Machine learning addresses many of the same research questions as the fields of statistics, data mining, and psychology, but with differences of emphasis. Statistics focuses on understanding the phenomena that have generated the data, often with the goal of testing different hypotheses about those phenomena. Data mining seeks to find patterns in the data that are understandable by people. Psychological studies of human learning aspire to understand the mechanisms underlying the various learning behaviors exhibited by people (concept learning, skill acquisition, strategy change, etc.).

Phd by thesis

Abstract: Deposits of clastic carbonate-dominated (calciclastic) sedimentary slope systems in the rock record have been identified mostly as linearly-consistent carbonate apron deposits, even though most ancient clastic carbonate slope deposits fit the submarine fan systems better. Calciclastic submarine fans are consequently rarely described and are poorly understood. Subsequently, very little is known especially in mud-dominated calciclastic submarine fan systems. Presented in this study are a sedimentological core and petrographic characterisation of samples from eleven boreholes from the Lower Carboniferous of Bowland Basin (Northwest England) that reveals a >250 m thick calciturbidite complex deposited in a calciclastic submarine fan setting. Seven facies are recognised from core and thin section characterisation and are grouped into three carbonate turbidite sequences. They include: 1) Calciturbidites, comprising mostly of highto low-density, wavy-laminated bioclast-rich facies; 2) low-density densite mudstones which are characterised by planar laminated and unlaminated muddominated facies; and 3) Calcidebrites which are muddy or hyper-concentrated debrisflow deposits occurring as poorly-sorted, chaotic, mud-supported floatstones. These