Luciano P. Silva

TL;DR: Drug delivery systems must be biocompatible, biodegradable, and display a desired biodistribution providing a long-term availability of the therapeutic at specific target over time.

TL;DR: In this paper, the size controlled synthesis of cobalt-ferrite nanoparticles, their passivation and peptization as stable ferrofluids, and the anomalous diffusion has been used to explain the nanoparticle size control mechanism.

TL;DR: DS 01 is a 29-residue-long peptide with a molecular mass of 2793 Da showing antibacterial properties against Gram-positive and Gram-negative bacteria in the range of 3-25 microm, suggesting its therapeutic value especially as an anti-T.

TL;DR: Six novel peptides called phylloseptins showing anti-bacterial and anti-protozoan activities were isolated from the skin secretion of the Brazilian tree-frogs and Phyllomedusa oreades, and Atomic force microscopy experiments indicated that the bacteriolytic properties of these peptides might be related to their disruptive action on the cell membrane.

TL;DR: Nine novel PE-degrading bacteria from plastic debris found in soil of the savanna-like Brazilian Cerrado are isolated, indicating that these microbes are capable of degrading unpretreated PE of very high molecular weight and survive for long periods under this condition, suggesting not only practical applications in waste management and environmental decontamination, but also future directions to understand the unraveled metabolism of synthetic polymers.