scispace - formally typeset
L

Ludo Van Den Bosch

Researcher at Katholieke Universiteit Leuven

Publications -  223
Citations -  20789

Ludo Van Den Bosch is an academic researcher from Katholieke Universiteit Leuven. The author has contributed to research in topics: Amyotrophic lateral sclerosis & Motor neuron. The author has an hindex of 58, co-authored 200 publications receiving 17197 citations. Previous affiliations of Ludo Van Den Bosch include Allen Institute for Brain Science & Catholic University of Leuven.

Papers
More filters
Journal ArticleDOI

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

Daniel J. Klionsky, +2522 more
- 21 Jan 2016 - 
TL;DR: In this paper, the authors present a set of guidelines for the selection and interpretation of methods for use by investigators who aim to examine macro-autophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.
Journal ArticleDOI

Protein Phase Separation: A New Phase in Cell Biology.

Steven Boeynaems, +15 more
- 01 Jun 2018 - 
TL;DR: A combination of techniques from cell biology, biophysics, physical chemistry, structural biology, and bioinformatics are starting to help establish the molecular principles of an emerging field, thus paving the way for exciting discoveries, including novel therapeutic approaches for the treatment of age-related disorders.
Journal ArticleDOI

Mutant small heat-shock protein 27 causes axonal Charcot-Marie-Tooth disease and distal hereditary motor neuropathy

Oleg V. Evgrafov, +25 more
- 02 May 2004 - 
TL;DR: A missense mutation in the gene encoding 27-kDa small heat-shock protein B1 (HSPB1, also called HSP27) that segregates in the family with CMT2F is reported and four additional missense mutations are identified.
Journal ArticleDOI

Treatment of motoneuron degeneration by intracerebroventricular delivery of VEGF in a rat model of ALS

Erik Storkebaum, +20 more
- 01 Jan 2005 - 
TL;DR: It is shown that intracerebroventricular delivery of Vegf in a SOD1G93A rat model of ALS delays onset of paralysis, improves motor performance and prolongs survival by 22 d, representing the largest effects in animal models of ALS achieved by protein delivery.
Journal ArticleDOI

Modifiers of C9orf72 dipeptide repeat toxicity connect nucleocytoplasmic transport defects to FTD/ALS

Ana Jovičić, +18 more
- 01 Sep 2015 - 
TL;DR: Two unbiased screens in Saccharomyces cerevisiae were performed and potent modifiers of DPR toxicity, including karyopherins and effectors of Ran-mediated nucleocytoplasmic transport were identified, providing insight into potential disease mechanisms and therapeutic targets.